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U.S. Patents Awarded to Inventors in Michigan (Sept. 8)
[September 08, 2012]

U.S. Patents Awarded to Inventors in Michigan (Sept. 8)


(Targeted News Service Via Acquire Media NewsEdge) Targeted News Service Targeted News Service ALEXANDRIA, Va., Sept. 8 -- The following federal patents were awarded to inventors in Michigan.

*** HHS, Progeria Research Foundation, University of North Carolina at Chapel Hill, University of Michigan Assigned Patent ALEXANDRIA, Va., Sept. 8 -- The U.S. Department of Health and Human Services, Progeria Research Foundation, Peabody, Mass., the University of North Carolina at Chapel Hill, Ann Arbor, Mich., and the University of Michigan, Ann Arbor, Mich., have been assigned a patent (8,257,915) developed by seven co-inventors for a "farnesyltransferase inhibitors for treatment of laminopathies, cellular aging and atherosclerosis." The co-inventors are Leslie B. Gordon, Foxboro, Mass., Francis S. Collins, Rockville, Md., Thomas Glover, Ypsilanti, Mich., Michael W. Glynn, Darien, Conn., Brian C. Capell, Rumson, N.J., Adrienne D. Cox, Chapel Hill, N.C., and Channing J. Der, Chapel Hill, N.C.



The abstract of the patent published by the U.S. Patent and Trademark Office states: "Although it can be farnesylated, the mutant lamin A protein expressed in Hutchinson Gilford Progeria Syndrome (HGPS) cannot be defarnesylated because the characteristic mutation causes deletion of a cleavage site necessary for binding the protease ZMPSTE24 and effecting defarnesylation. The result is an aberrant farnesylated protein (called "progerin") that alters normal lamin A function as a dominant negative, as well as assuming its own aberrant function through its association with the nuclear membrane. The retention of farnesylation, and potentially other abnormal properties of progerin and other abnormal lamin gene protein products, produces disease. Farnesyltransferase inhibitors (FTIs) (both direct effectors and indirect inhibitors) will inhibit the formation of progerin, cause a decrease in lamin A protein, and/or an increase prelamin A protein. Decreasing the amount of aberrant protein improves cellular effects caused by and progerin expression. Similarly, treatment with FTIs should improve disease status in progeria and other laminopathies. In addition, elements of atherosclerosis and aging in non-laminopathy individuals will improve after treatment with farnesyltransferase inhibitors." The patent application was filed on Oct. 15, 2010 (12/905,838). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,257,915.PN.&OS=PN/8,257,915&RS=PN/8,257,915 Written by Kusum Sangma; edited by Anand Kumar.

*** A123 Systems Assigned Patent ALEXANDRIA, Va., Sept. 8 -- A123 Systems, Waltham, Mass., has been assigned a patent (8,257,855) developed by Mujeeb Ijaz, Leonard, Mich., Jonathan E. Hostler, Canton, Mich., and Shazad M. Butt, Troy, Mich., for a "prismatic battery module with scalable architecture." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A battery system including: a plurality of subunits each of which has a heatsink and a battery cell and two voltage terminals symmetrically positioned with respect to a centerline of that battery cell, wherein all of the battery cells are arranged so that their voltage terminals are aligned along two rows; a plurality of identical busbar supports equal in number to the plurality of subunits, each having two slots and mounted on a corresponding different one of the subunits with each of the terminals of the battery cell extending up through the two slots; and a plurality of bimetallic busbars, each one supported by a different corresponding subset of the busbar supports and electrically connected directly to either a first or second terminal of each of the battery cells of each of the modules on which those busbar supports are mounted." The patent application was filed on Dec. 1, 2009 (12/628,809). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,257,855.PN.&OS=PN/8,257,855&RS=PN/8,257,855 Written by Kusum Sangma; edited by Anand Kumar.


*** A123 Systems Assigned Patent for Safety Venting Mechanism with Tearing Tooth Structure for Batteries ALEXANDRIA, Va., Sept. 8 -- A123 Systems, Waltham, Mass., has been assigned a patent (8,257,848) developed by five co-inventors for a "safety venting mechanism with tearing tooth structure for batteries." The co-inventors are Mujeeb Ijaz, Leonard, Mich., Shazad M. Butt, Troy, Mich., Whanjin Roh, Seoul, South Korea, Jonathan E. Hostler, Canton, Mich., and Myoungshin Hong, Seongnam, South Korea.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A battery comprises a battery cell having two voltage terminals and a flexible sidewall; a wall structure against which the battery cell is located, the wall structure including a sidewall that is adjacent to the sidewall of the battery cell; and a tooth structure that extends away from the sidewall of the wall structure and towards the sidewall of the battery cell, wherein the tooth structure includes a distal end sufficiently sharp to puncture the flexible sidewall of the battery cell when the flexible sidewall of the battery cell is forced up against the tooth structure due to a build up of excess pressure inside the battery cell." The patent application was filed on Dec. 1, 2009 (12/628,713). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,257,848.PN.&OS=PN/8,257,848&RS=PN/8,257,848 Written by Kusum Sangma; edited by Anand Kumar.

*** GM Global Technology Operations Assigned Patent ALEXANDRIA, Va., Sept. 8 -- GM Global Technology Operations, Detroit, has been assigned a patent (8,257,883) developed by Youssef M. Mikhail, Sterling Heights, Mich., Mahmoud H. Abd Elhamid, Grosse Pointe Woods, Mich., and Gayatri Vyas, Rochester Hills, Mich., for a "durability for the MEA and bipolar plates in PEM fuel cells using hydrogen peroxide decomposition catalysts." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A fuel cell that employs a decomposition catalyst on one or more of the membrane, bipolar plates or diffusion media layers in the fuel cell that decomposes hydrogen peroxide, and thus reduces the generation of hydroxyl free radicals. In one embodiment, the decomposition catalyst is ruthenium oxide and is deposited on the structure by various processes, such as chemical vapor deposition process." The patent application was filed on Aug. 3, 2005 (11/196,632). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,257,883.PN.&OS=PN/8,257,883&RS=PN/8,257,883 Written by Kusum Sangma; edited by Anand Kumar.

*** Siemens Energy Assigned Patent ALEXANDRIA, Va., Sept. 8 -- Siemens Energy, Orlando, Fla., has been assigned a patent (8,257,809) developed by four co-inventors for a "CMC wall structure with integral cooling channels." The co-inventors are Jay A. Morrison, Oviedo, Fla., Douglas A. Keller, Kalamazoo, Mich., Malberto F. Gonzalez, Orlando, Fla., and Jay E. Lane, Mims, Fla.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A ceramic matrix composite wall structure (20A) constructed of interlocking layers (22A, 24A) of woven material with integral cooling channels (28A, 32A). The CMC layer closest to the hot gas path (41) contains internal cooling tubes (26A, 30A) protruding into a ceramic insulating layer (40A). This construction provides a cooled CMC lamellate wall structure with an interlocking truss core." The patent application was filed on March 8, 2007 (11/715,678). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,257,809.PN.&OS=PN/8,257,809&RS=PN/8,257,809 Written by Kusum Sangma; edited by Anand Kumar.

*** CertainTeed Assigned Patent ALEXANDRIA, Va., Sept. 8 -- CertainTeed, Valley Forge, Pa., has been assigned a patent (8,257,811) developed by five co-inventors for a composite building product. The co-inventors are Joong Youn Kim, Newtown Square, Pa., Thomas Kevin MacKinnon, Ann Arbor, Mich., Richard Allan Snyder, Eagleville, Pa., Husnu M. Kalkanoglu, Swarthmore, Pa., and Gregory F. Jacobs, Oreland, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A simultaneously molded plurality of composite shingles or double walled shingles or other substantially planar exterior building products are provided, each being comprised of two or more layers of thermoplastic shingle material, such that a weatherable capstock material is provided outside a core material, in the form of a composite parison that is then blow molded in a hollow mold, to produce novel shingles. Ventilation and/or insulation can be provided to a hollow interior between spaced apart walls of a double walled shingle." The patent application was filed on March 28, 2006 (11/390,590). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,257,811.PN.&OS=PN/8,257,811&RS=PN/8,257,811 Written by Kusum Sangma; edited by Anand Kumar.

*** Corning Assigned Patent ALEXANDRIA, Va., Sept. 8 -- Corning, Corning, N.Y., has been assigned a patent (8,257,965) developed by five co-inventors for "arrays of biological membranes and methods and use thereof." The co-inventors are Ye Fang, Painted Post, N.Y., Anthony G. Frutos, Painted Post, N.Y., Steven J. Jonas, Bloomfield Hills, Mich., Peter J. Kalal, Corning, N.Y., and Joydeep Lahiri, Painted Post, N.Y.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention overcomes the problems and disadvantages associated with prior art arrays by providing an array comprising a plurality of biological membrane microspots associated with a surface of a substrate that can be produced, used and stored, not in an aqueous environment, but in an environment exposed to air under ambient or controlled humidities. Preferably, the biological membrane microspots comprise a membrane bound protein. Most preferably, the membrane bound protein is a G-protein coupled receptor, an ion channel, a receptor serine/threonine kinase or a receptor tyrosine kinase." The patent application was filed on Jan. 29, 2010 (12/696,622). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,257,965&OS=8,257,965&RS=8,257,965 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** GM Global Technology Operations Assigned Patent for Method for Characterizing the Porosity in Fuel Cell Electrodes ALEXANDRIA, Va., Sept. 8 -- GM Global Technology Operations, Detroit, has been assigned a patent (8,257,979) developed by Michael P. Balogh, Novi, Mich., and Frederick A. Hayes, Dixon, Calif., for a "method for characterizing the porosity in fuel cell electrodes." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A method for evaluating the composition of an MEA for a fuel cell. The method includes soaking the MEA in an unsaturated organic compound for a predetermined period of time, and then allowing the MEA to dry. The method then includes staining the MEA with osmium tetroxide (OsO.sub.4) in a closed container. The stained MEA is then encased in an epoxy. Thin sections of the encapsulated MEA are then prepared, and the sections are viewed through a transmission electron microscope. The stained MEA will show dark regions where the ionomer and carbon particles are located and lighter regions that are epoxy filled pores." The patent application was filed on Nov. 12, 2007 (11/938,521). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,257,979&OS=8,257,979&RS=8,257,979 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Sun Drilling Products Assigned Patent ALEXANDRIA, Va., Sept. 8 -- Sun Drilling Products, Belle Chasse, La., has been assigned a patent (8,258,083) developed by Jozef Bicerano, Midland, Mich., for a "method for the fracture stimulation of a subterranean formation having a wellbore by using impact-modified thermoset polymer nanocomposite particles as proppants." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A method for fracture stimulation of a subterranean formation includes providing a thermoset polymer nanocomposite particle precursor composition comprising a polymer precursor mixture, dispersed within a liquid medium, containing at least one of an initiator; at least one of a monomer, an oligomer or combinations thereof, said monomer and oligomer having three or more reactive functionalities capable of creating crosslinks between polymer chains; at least one of an impact modifier; and nanofiller particles substantially dispersed within the liquid medium; subjecting the nanocomposite particle precursor composition to suspension polymerizing conditions; subjecting the resulting nanocomposite particles to heat treatment; forming a slurry comprising a fluid and a proppant that includes the heat-treated nanocomposite particles; injecting the slurry into a wellbore; and emplacing the proppant within a fracture network in the formation." The patent application was filed on April 3, 2007 (11/695,745). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,258,083&OS=8,258,083&RS=8,258,083 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Duquesne University, Wayne State University Assigned Patent ALEXANDRIA, Va., Sept. 8 -- Duquesne University, Pittsburgh, and Wayne State University, Detroit, have been assigned a patent (8,258,143) developed by Aleem Gangjee, Allison Park, Pa., and Larry H. Matherly, Farmington Hills, Mich., for "methods of using substituted pyrrolo[2,3-d]pyrimidines for targeting tumor cells and treating cancer." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A method for treating cancer tumors, particularly ovarian cancer tumors, is described, where fused cyclic pyrimidine having a cancer treating ability is selectively delivered to an FR expressing cancerous tumor." The patent application was filed on June 21, 2007 (11/820,872). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,258,143&OS=8,258,143&RS=8,258,143 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Rohm and Haas Electronic Assigned Patent for Method of Making Light Emitting Diodes ALEXANDRIA, Va., Sept. 8 -- Rohm and Haas Electronic Materials, Marlborough, Mass., has been assigned a patent (8,257,988) developed by four co-inventors for "method of making light emitting diodes." The co-inventors are Paul Joseph Popa, Auburn, Mich., Garo Khanarian, Princeton, N.J., Weijun Zhou, Sugar Land, Texas, and John R. Ell, Quakertown, Pa.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A method of making a light emitting diode (LED) having an optical element is provided, comprising: providing a curable liquid polysiloxane/TiO.sub.2 composite, which exhibits a refractive index of >1.61 to 1.7 and which is a liquid at room temperature and atmospheric pressure; providing a semiconductor light emitting diode die having a face, wherein the semiconductor light emitting diode die emits light through the face; contacting the semiconductor light emitting diode die with the curable liquid polysiloxane/TiO.sub.2 composite; and, curing the curable liquid polysiloxane/TiO.sub.2 composite to form an optical element; wherein at least a portion of the optical element is adjacent to the face." The patent application was filed on May 17, 2011 (13/109,053). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,257,988&OS=8,257,988&RS=8,257,988 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** DexCom Assigned Patent ALEXANDRIA, Va., Sept. 8 -- DexCom, San Diego, has been assigned a patent (8,257,259) developed by six co-inventors for a "signal processing for continuous analyte sensor." The co-inventors are James H. Brauker, Cement City, Mich., Victoria E. Carr-Brendel, San Diego, Paul V. Goode, Cherry Hill, N.J., Apurv Ullas Kamath, San Diego, James Patrick Thrower, Oakland, N.J., and Ben Xavier, San Diego.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk." The patent application was filed on Oct. 16, 2008 (12/252,952). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=82,57,259.PN.&OS=PN/82,57,259&RS=PN/82,57,259 Written by Shabnam Sheikh; edited by Jaya Anand.

*** Thompson Surgical Instruments Assigned Patent ALEXANDRIA, Va., Sept. 8 -- Thompson Surgical Instruments, Traverse City, Mich., has been assigned a patent (8,257,255) developed by Daniel K. Farley, Traverse City, Mich., and Steven Nowak, Traverse City, Mich., for a "surgical retractor with locking blade." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Certain embodiments provide surgical retractors that include an arm and a blade, the arm including an opening and a first notched surface comprising a plurality of notches that extend radially outward from the opening, the blade including a nipple and a second notched surface comprising a plurality of notches that extend radially outward from the nipple. Attaching the blade to the arm such that the notched surfaces mate can secure the blade relative to the arm such that the blade cannot swivel radially about the opening. Certain embodiments provide methods for securing a retractor blade that can include inserting a nipple on a retractor blade into an opening and mating a first notched surface comprising a plurality of notches that extend radially outward from the opening with a second notched surface comprising a plurality of notches that extend radially outward from the nipple." The patent application was filed on Feb. 24, 2009 (12/391,917). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=82,57,255.PN.&OS=PN/82,57,255&RS=PN/82,57,255 Written by Shabnam Sheikh; edited by Jaya Anand.

*** Linares Medical Devices Assigned Patent ALEXANDRIA, Va., Sept. 8 -- Linares Medical Devices, Auburn Hills, Mich., has been assigned a patent (8,257,290) developed by Miguel A. Linares, Bloomfield Hills, Mich., for a "temporary splint assembly with semi-rigid wrap around supports in combination with intermediately positioned joint cast." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A splint assembly for use with an individual's limb including an assembleable and rigid member positioned in surrounding fashion about an intermediate joint associated with the limb. A pair of support subassemblies secure about a location of the individual's limb contiguous to the joint, an extending edge of each support subassembly securing to a perimeter extending edge of the rigid member. Upper and lower wraparound support subassemblies secure to first and second perimeter extending edges associated with the rigid member, each further including a generally grid and web-shaped foam template with a hardened plastic backing being configured to match the configuration of the foam template. Edge extending straps provided for each of the hardened plastic backings overlap and engage opposite extending edge locations of each wraparound support subassembly." The patent application was filed on Sept. 4, 2009 (12/554,179). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=82,57,290.PN.&OS=PN/82,57,290&RS=PN/82,57,290 Written by Shabnam Sheikh; edited by Jaya Anand.

*** Linares Medical Devices Assigned Patent for Neck Cast with Multi-position Adjustability of Height and Diameter and Including Downwardly Configured Shoulder Supports ALEXANDRIA, Va., Sept. 8 -- Linares Medical Devices, Auburn Hills, Mich., has been assigned a patent (8,257,292) developed by Miguel A. Linares, Bloomfield Hills, Mich., for a "neck cast with multi-position adjustability of height and diameter and including downwardly configured shoulder supports for immobilizing a patient's head." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention teaches a head and neck cast for providing secure immobilization of a patient's upper neck and head extremities and includes a lower ergonomically configured ring supported upon the shoulders of the wearer. An upper ring is vertically displaceable in each of upper and lower directions relative to the lower support ring via an interconnecting network of both scissoring and vertically extending jacks. In this fashion, the neck and head of the patient is immobilized via the positional support provided by the lower ring and without the need for screws mounted to the skull." The patent application was filed on Oct. 5, 2009 (12/573,299). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=82,57,292.PN.&OS=PN/82,57,292&RS=PN/82,57,292 Written by Shabnam Sheikh; edited by Jaya Anand.

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