U.S. Patents Awarded to Inventors in California (Jan. 19)

(Targeted News Service Via Acquire Media NewsEdge) Targeted News Service Targeted News Service ALEXANDRIA, Va., Jan. 19 -- The following federal patents were awarded to inventors in California.

*** Genentech Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Genentech, South San Francisco, Calif., has been assigned a patent (8,354,420) developed by 11 co-inventors for "aminopyrimidine derivatives as LRRK2 inhibitors." The co-inventors are Charles Baker-Glenn, Puckeridge, United Kingdom, Daniel Jon Burdick, Burlingame, Calif., Mark Chambers, St. Neots, United Kingdom, Bryan K. Chan, Burlingame, Calif., Huifen Chen, Burlingame, Calif., Anthony Estrada, San Carlos, Calif., Janet Gunzner-Toste, Piedmont, Calif., Daniel Shore, San Francisco, Zachary Sweeney, Redwood City, Calif., Shumei Wang, Foster City, Calif., and Guiling Zhao, San Mateo, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Compounds of the formula I: ##STR00001## or pharmaceutically acceptable salts thereof, wherein m, n. X, R.sup.1, R.sup.2, R.sup.3, R.sup.5, R.sup.6 and R.sup.7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease." The patent application was filed on June 1, 2011 (13/150,929). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,420&OS=8,354,420&RS=8,354,420 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Metabolex Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Metabolex, Hayward, Calif., has been assigned a patent (8,354,448) developed by Kenneth L. Luskey, Saratoga, Calif., and Jian Luo, Brisbane, Calif., for an "use of (-)(3-trihalomethylphenoxy)(4-halophenyl) acetic acid derivatives for treatment of type 2 diabetes." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides the use of (-)(3-trihalomethylphenoxy)(4-halophenyl)acetic acid derivatives and compositions in the treatment of insulin resistance, Type 2 diabetes and hyperlipidemia." The patent application was filed on July 16, 2009 (12/504,487). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,448&OS=8,354,448&RS=8,354,448 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Vertex Pharmaceuticals Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Vertex Pharmaceuticals, Cambridge, Mass., has been assigned a patent (8,354,419) developed by 22 co-inventors for "benzimidazole analogues for the treatment or prevention of flavivirus infections." The co-inventors are James A. Henderson, Cambridge, Mass., John Maxwell, Hingham, Mass., Louis Vaillancourt, Mascouche, Canda, Mark Morris, Somerville, Mass., Ronald Grey Jr., Attleboro, Mass., Simon Giroux, Cambridge, Mass., Laval Chan Chun Kong, Kirkland, Calif., Sanjoy Kumar Das, Pierrefonds, Canada, Bingcan Liu, Montreal, Carl Poisson, Montreal, Caroline Cadilhac, Montreal, Monica Bubenik, Mascouche, Canada, T. Jagadeeswar Reddy, Pierrefonds, Canada, Guy Falardeau, Laval, Canada, Constantin Yannopoulos , Notre-Dame de l'lle Perrot, Canada, Jian Wang, Newton, Mass., Oswy Z. Pereira, Kirkland, Calif., Youssef L. Bennani, Boston, Albert C. Pierce, Cambridge, Mass., Govinda Rao Bhisetti, Lexington, Mass., Kevin M. Cottrell, Cambridge, Mass., and Valerie Marone, Waltham, Mass.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Compounds represented by formula I: ##STR00001## or pharmaceutically acceptable salts and solvates thereof, wherein A, B, B', X, Y, R.sub.1, R.sub.1', R.sub.2, R.sub.2', R.sub.3, R.sub.3', R.sub.5, R.sub.5', R.sub.6, m, n, or p are as defined herein, are useful for treating flaviviridae viral infections." The patent application was filed on July 16, 2010 (12/838,350). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,419&OS=8,354,419&RS=8,354,419 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Scripps Research Institute Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Scripps Research Institute, La Jolla, Calif., has been assigned a patent (8,354,447) developed by four co-inventors for "mGLU receptors antagonists for treating disorders associated with mGLU receptors including addiction and depression." The co-inventors are Athina Markou, Del Mar, Calif., Paul Kenny, San Diego, Neil Paterson, Encinitas, Calif., and Svetlana Semenova, Carlsbad, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Methods are provided for treating disorders associated with mGlu receptors by simultaneously inhibiting at least two mGluRs belonging to at least two different groups. In one embodiment, there are provided methods for treating a disorder associated with mGlu receptors 2, 3, and 5, including administering to a subject in need thereof an effective amount of at least one antagonist which modulates mGluR2, mGluR3, and mGluRS. The disorders treated by the method include, for example, nicotine addiction, cocaine addiction, and depression." The patent application was filed on Sept. 10, 2003 (10/527,525). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,447&OS=8,354,447&RS=8,354,447 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Allergan Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Allergan, Irvine, Calif., has been assigned a patent (8,354,409) developed by four co-inventors for a "combination of brimonidine and timolol for topical ophthalmic use." The co-inventors are Chin-Ming Chang, Tustin, Calif., Gary J. Beck, Fullerton, Calif., Cynthia C. Pratt, Mission Viejo, Calif., and Amy L. Batoosingh, Mission Viejo, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Disclosed are pharmaceutical compositions comprising brimondine and timolol for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for glaucoma and associated conditions such as elevated intraocular pressure in the eyes of humans." The patent application was filed on Nov. 30, 2011 (13/308,507). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,409&OS=8,354,409&RS=8,354,409 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Lawrence Livermore National Security Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Lawrence Livermore National Security, Livermore, Calif., has been assigned a patent (8,354,514) developed by five co-inventors for "multiplex detection of agricultural pathogens." The co-inventors are Thomas R. Siezak, Livermore, Calif., Shea Gardner, Oakland, Calif., Clinton Torres, Pleasanton, Calif., Elizabeth Vitalis, Livermore, Calif., and Raymond J. Lenhoff, Livermore, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Described are kits and methods useful for detection of agricultural pathogens in a sample. Genomic sequence information from agricultural pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay and/or an array assay to successfully identify the presence or absence of pathogens in a sample." The patent application was filed on July 23, 2010 (12/842,952). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,514&OS=8,354,514&RS=8,354,514 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Diadexus Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Diadexus, South San Francisco, Calif., has been assigned a patent (8,354,508) developed by four co-inventors for "PRO115 antibody compositions and methods of use." The co-inventors are Gundo Diedrich, South San Francisco, Calif., Paul Levi Miller, South San Francisco, Calif., Jackie Papkoff, San Francisco, and Astrid Strelow, Redwood City, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention provides isolated anti-Pro115 antibodies that bind to Pro115. The invention also encompasses compositions comprising an anti-Pro115 antibody and a carrier. These compositions can be provided in an article of manufacture or a kit. Another aspect of the invention is an isolated nucleic acid encoding an anti-Pro115 antibody, as well as an expression vector comprising the isolated nucleic acid. Also provided are cells that produce the anti-Pro115 antibodies. The invention encompasses a method of producing the anti-Pro115 antibodies. Other aspects of the invention are a method of killing an Pro115-expressing cancer cell, comprising contacting the cancer cell with an anti-Pro115 antibody and a method of alleviating or treating an Pro115-expressing cancer in a mammal, comprising administering a therapeutically effective amount of the anti-Pro115 antibody to the mammal." The patent application was filed on July 20, 2007 (12/374,292). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,508&OS=8,354,508&RS=8,354,508 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** MannKind Assigned Patent ALEXANDRIA, Va., Jan. 19 -- MannKind, Valencia, Calif., has been assigned a patent (8,354,380) developed by Liping Liu, Manassas, Va., Adrian Bot, Valencia, Calif., and David C. Diamond, West Hills, Calif., for NY-ESO-1 peptide analogs.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Some embodiments relate to analogs of peptides corresponding to class I MHC-restricted T cell epitopes and methods for their generation. These analogs can contain amino acid substitutions at residues that directly interact with MHC molecules, and can confer improved, modified or useful immunologic properties. Additionally classes of analogs, in which the various substitutions comprise the non-standard residues norleucine and/or norvaline, are disclosed." The patent application was filed on June 17, 2005 (11/155,929). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,380&OS=8,354,380&RS=8,354,380 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Temptime Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Temptime, Morris Plains, N.J., has been assigned a patent (8,354,486) developed by seven co-inventors for "co-crystallizable diacetylenic monomer compositions, crystal phases and mixtures, and related methods." The co-inventors are Elizabeth Castillo Martinez, Dallas, Ray H. Baughman, Dallas, Lee J. Hall, Glendale, Calif., Mikhail Kozlov, Dallas, Dawn E. Smith, Martinsville, N.J., Thaddeus Prusik, Stroudsburg, Pa., and Carl M. Lentz, Cedar Knolls, N.J.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Solid polymerizable diacetylenic monomer compositions, including compositions co-crystallized from a diversity of solvent systems under diverse cooling conditions, can exhibit diffraction patterns associated with the color development reactivities of the compositions. High reactivity compositions are disclosed and high reactivity and low reactivity phases can be identified. A low angle powder X-ray diffraction peak can indicate the presence of one or more crystal phases in a composition. A fingerprint region can exhibit fingerprint patterns of diffraction peaks associated with different reactivities. Information about polymerization of the diacetylenic monomers is disclosed using .sup.13C nuclear magnetic resonance ("NMR") characterization. Diacetylenic monomer compositions useful in ambient condition indicators, for example time-temperature indicators are disclosed." The patent application was filed on March 24, 2010 (12/730,835). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,486&OS=8,354,486&RS=8,354,486 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Bristol-Myers Squibb Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Bristol-Myers Squibb, Princeton, N.J., has been assigned a patent (8,354,513) developed by Glen Eugene Mikesell, Pacifica, Calif., Han Chang, Princeton Junction, N.J., and Robert James Peach, San Diego, for polynucleotides encoding BSL2vcvc-lg.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides nucleic acids encoding B7-related factors that modulate the activation of immune or inflammatory response cells, such as T-cells. Also provided are expression vectors and fusion constructs comprising nucleic acids encoding B7-related polypeptides, including BSL1, BSL2, and BSL3. The present invention further provides isolated B7-related polypeptides, isolated fusion proteins comprising B7-related polypeptides, and antibodies that are specifically reactive with B7-related polypeptides, or portions thereof. In addition, the present invention provides assays utilizing B7-related nucleic acids, polypeptides, or peptides. The present invention further provides compositions of B7-related nucleic acids, polypeptides, fusion proteins, or antibodies that are useful for the immunomodulation of a human or animal subject." The patent application was filed on May 20, 2010 (12/783,968). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,513&OS=8,354,513&RS=8,354,513 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Clorox Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Clorox, Oakland, Calif., has been assigned a patent (8,354,364) developed by four co-inventors for a "foamable composition containing alcohol." The co-inventors are David Lestage, Livermore, Calif., David R. Scheuing, Danville, Calif., Scott L. Cumberland, Pleasanton, Calif., and Grant Templin, Dublin, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "This invention relates to compositions containing lower (C1-C4) alcohol and a polymeric fluorosurfactant formulated for being dispensed as a foam product. More particularly, the invention relates to improved compositions formulated with polymeric fluorosurfactants with pendant perfluoroalkyl side chains of a fully fluorinated chain length of C1-C7. The compositions also relate to use for personal care, such as skin sanitizing and cleansing." The patent application was filed on April 2, 2010 (12/753,498). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,364&OS=8,354,364&RS=8,354,364 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Vertex Pharmaceutical Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Vertex Pharmaceutical, Cambridge, Mass., has been assigned a patent (8,354,427) developed by Fredrick Van Goor, San Diego, for "modulators of ATP-binding cassette transporters." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators." The patent application was filed on Dec. 11, 2009 (12/635,927). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,427&OS=8,354,427&RS=8,354,427 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Ligand Pharmaceuticals Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Ligand Pharmaceuticals, La Jolla, Calif., has been assigned a patent (8,354,446) developed by Lin Zhi, San Diego, for "selective androgen receptor modulators (SARMs) and uses thereof." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Provided herein are compounds of formulae I to II that bind to androgen receptors and/or modulate activity of androgen receptors; and to methods for making and using such compounds. Also provided are compositions including such compounds and methods for making and using such compositions. ##STR00001##." The patent application was filed on Dec. 12, 2008 (12/734,993). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,446&OS=8,354,446&RS=8,354,446 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Harbor Therapeutics Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Harbor Therapeutics, San Diego, has been assigned a patent (8,354,396) developed by James M. Frincke, Carlsbad, Calif., and Christopher Reading, San Diego, for a "drug identification and treatment method." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention relates to methods to identify compounds that can treat autoimmune conditions and treat specified clinical disorders such as multiple sclerosis, ulcerative colitis or arthritis. Compounds include 17.alpha.-ethynylandrost-5-ene-3.beta.,11.beta.,7.alpha.,17.beta.-tetrol, 4.alpha.-acetoxy-17.alpha.-ethynylandrost-5-ene-3.beta.,7.beta.,17.beta.-- triol, 17.alpha.-ethynylandrost-5-ene-3.beta.,4.beta.,7.alpha.,17.beta.-te- trol, 17.alpha.-ethynylandrost-5-ene-3.alpha.,4.beta.,7.alpha.,17.beta.-te- trol and 17.alpha.-ethynylandrost-5-ene-3.alpha.,4.beta.,17.beta.-triol-7-- one." The patent application was filed on Nov. 17, 2007 (11/941,936). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,396&OS=8,354,396&RS=8,354,396 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Stanford University Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Stanford University, Palo Alto, Calif., has been assigned a patent (8,354,435) developed by Che-Hong Chen, Fremont, Calif., Daria Mochly-Rosen, Menlo Park, Calif., and Wenjin Yang, Foster City, Calif., for "modulators of aldehyde dehydrogenase activity and methods of use thereof." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides compounds that function as modulators of aldehyde dehydrogenase activity; and pharmaceutical compositions comprising the compounds. The present invention provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition." The patent application was filed on Sept. 3, 2009 (12/553,805). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,354,435&OS=8,354,435&RS=8,354,435 Written by Satyaban Rath; edited by Hemanta Panigrahi.

*** Medtronic Vascular Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Medtronic Vascular, Santa Rosa, Calif., has been assigned a patent (8,353,952) developed by seven co-inventors for a "stent with therapeutic substance." The co-inventors are Dustin Thompson, Santa Rosa, Calif., Paul Adler, Santa Rosa, Calif., Maria Arreguin, Windsor, Calif., Kevin Mauch, Windsor, Calif., Christopher Storment, Sonoma, Calif., Lance Ensign, Santa Rosa, Calif., and Stephen Zimmerman, Healdsburg, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A stent includes a wave form that includes a cable including a plurality of strands. The wave form has a plurality of struts and a plurality of crowns, with each crown connecting two adjacent struts. The wave form is wrapped around a longitudinal axis at a pitch to define a plurality of helical turns. The stent includes a filler located within the cable. The filler includes a therapeutic substance." The patent application was filed on April 7, 2010 (12/755,562). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,952.PN.&OS=PN/83,53,952&RS=PN/83,53,952 Written by Amal Ahmed; edited by Jaya Anand.

*** St. Jude Medical Assigned Patent ALEXANDRIA, Va., Jan. 19 -- St. Jude Medical, St. Paul, Minn., has been assigned a patent (8,353,954) developed by six co-inventors for a "prosthetic heart valve including stent structure and tissue leaflets, and related methods." The co-inventors are Chad Cai, Woodbury, Minn., Peter Nicholas Braido, Maple Grove, Minn., Bob Allan, Maple Grove, Minn., Paul Edward Ashworth, Wyoming, Minn., Steve Kruse, St. Michael, Minn., and Lise LaChance, Santa Rosa, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A prosthetic heart valve includes an annular stent having annularly spaced commissure portions. The tips of the commissure portions are preferably covered with fabric, and then additional fabric covers that fabric and the remainder of the stent, both inside and out (possibly also including a sewing ring insert at or near the base or inflow edge). The fabric is then covered by a layer of tissue, again both inside and out. A single sheet of additional tissue is mounted around the outside of the previously assembled components. This additional tissue forms the leaflet portions of the valve. The leaflet portions of the additional tissue are shaped by contact with a shaped mandrel, and the tissue of the structure is subjected to fixation (e.g., cross-linking) to produce a completed valve." The patent application was filed on Dec. 19, 2007 (12/004,170). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,954.PN.&OS=PN/83,53,954&RS=PN/83,53,954 Written by Amal Ahmed; edited by Jaya Anand.

*** Springboard Medical Ventures Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Springboard Medical Ventures, Laguna Hills, Calif., has been assigned a patent (8,353,940) developed by Theodore V. Benderev, Laguna Hills, Calif., for a "system and method for securing implants to soft tissue." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Self-anchoring slings and deployment mechanisms for use therewith in selectively positioning a sling into position within the body. According to a preferred embodiment, a system is provided for securing a sling into fixed position within a target site of soft tissue within the body. The system includes an implantable sling having an elongate segment of material with an anchor mechanism formed on the ends thereof. The system also includes a non-mechanically assisted deployment mechanism for positioning the anchor mechanisms within the target site. The deployment mechanism has a manually operable handle having a deployment member extending distally therefrom, the deployment member being detachably fastenable to a respective one of said anchor mechanisms of said implantable sling. The deployment member is configured to guide the anchor mechanism through the soft tissue to the target site, and insert said anchor mechanism into said tissue at said target site." The patent application was filed on Feb. 13, 2008 (12/069,858). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,940.PN.&OS=PN/83,53,940&RS=PN/83,53,940 Written by Amal Ahmed; edited by Jaya Anand.

*** Invention Science Fund I Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Invention Science Fund I, Bellevue, Wash., has been assigned a patent (8,353,896) developed by eight co-inventors for a "controllable release nasal system." The co-inventors are W. Daniel Hillis, Encino, Calif., Roderick A. Hyde, Livermore, Calif., Muriel Y. Ishikawa, Livermore, Calif., Elizabeth A. Sweeney, Seattle, Clarence T. Tegreene, Bellevue, Wash., Richa Wilson, San Francisco, Lowell L. Wood Jr., Livermore, Calif., and Victoria Y. H. Wood, Livermore, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Embodiments of devices and system for controllable nasal delivery of materials are described. Methods of use of such devices and system and software for controlling the operation of such devices and systems are also disclosed." The patent application was filed on May 4, 2006 (11/417,898). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,896.PN.&OS=PN/83,53,896&RS=PN/83,53,896 Written by Amal Ahmed; edited by Jaya Anand.

*** Zoll Circulation Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Zoll Circulation, Sunnyvale, Calif., has been assigned a patent (8,353,893) developed by Kenneth A. Collins, Mission Viejo, Calif., for a "system and method for rapidly cooling cardiac arrest patient." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A combined occlusion/infusion catheter is placed in the aorta of a cardiac arrest patient to occlude the aorta at a location just above the renal arteries/celiac trunk while rapidly infusing a liter or more of cold saline into the aorta below the occlusion. This flushes white cells from the bowel (now placed into a state of hypothermic stasis) induces hypothermia in the whole body, with perfusion pressure of the cold fluid maximized to the brain." The patent application was filed on March 7, 2007 (11/715,102). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,893.PN.&OS=PN/83,53,893&RS=PN/83,53,893 Written by Amal Ahmed; edited by Jaya Anand.

*** J.W. Medical System Assigned Patent ALEXANDRIA, Va., Jan. 19 -- J.W. Medical System, Los Altos, Calif., has been assigned a patent (8,353,945) developed by seven co-inventors for a "delivery catheter having active engagement mechanism for prosthesis." The co-inventors are Bernard H. Andreas, Redwood City, Calif., Matthew McDonald, Santa Cruz, Calif., Jay S. Daulton, Gilroy, Calif., Andrew Leopold, Hawthorn Woods, Ill., Philip Leopold, North Barrington, Ill., Matt Maulding, Bellemont, Ariz., and Andrew Black, Round Lake, Ill.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Delivery catheters and systems are adapted for delivering multiple discreet prostheses in body lumens. An exemplary delivery catheter comprises a sheath, a pusher for moving the prostheses relative to the sheath, and a valve member for selectively retaining the prostheses in the sheath. For balloon expandable stents, an elongated shaft and an expandable member are slidably disposed in the sheath, and the prostheses are positionable on the expandable member for deployment in the body lumen. The valve member allows a selected number of prostheses to be deployed from the sheath while retaining other prostheses within the sheath." The patent application was filed on April 13, 2007 (11/735,400). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,945.PN.&OS=PN/83,53,945&RS=PN/83,53,945 Written by Amal Ahmed; edited by Jaya Anand.

*** Vivant Medical Assigned Patent for Energy Delivery Conduits for Use with Electrosurgical Devices ALEXANDRIA, Va., Jan. 19 -- Vivant Medical, Boulder, Colo., has been assigned a patent (8,353,901) developed by Francesca Rossetto, Longmont, Colo., Mani N. Prakash, Boulder, Colo., and Brian Shiu, Sunnyvale, Calif., for "energy delivery conduits for use with electrosurgical devices." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A conduit assembly for transmitting energy between an electrosurgical energy generator and an energy delivering device comprises a first cable sub-assembly including a cable having a flexibility and an energy attenuation; a second cable sub-assembly including a cable having a flexibility and an energy attenuation; wherein the flexibility of the cable of the first cable sub-assembly is less than the flexibility of the cable of the second cable sub-assembly; and wherein the energy attenuation of the cable of the first cable sub-assembly is less than the energy attenuation of the cable of the second cable sub-assembly." The patent application was filed on May 22, 2007 (11/805,052). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,901.PN.&OS=PN/83,53,901&RS=PN/83,53,901 Written by Amal Ahmed; edited by Jaya Anand.

*** Medtronic Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Medtronic, Minneapolis, has been assigned a patent (8,353,921) developed by six co-inventors for a "tissue connector apparatus and methods." The co-inventors are Laurent Schaller, Los Altos, Calif., Barry Gardiner, Orinda, Calif., Art Hill, San Francisco, John Nguyen, San Jose, Calif., Liem Ho, Mountain View, Calif., and Isidro Matias Gandionco, Fremont, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Tissue connector assemblies having at least two piercing members, each releaseably coupled to a surgical fastener such as a surgical clip. A flexible member such as a suture may be used to couple one or both piercing members to respective ends of the fastener." The patent application was filed on Aug. 4, 2010 (12/849,861). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,921.PN.&OS=PN/83,53,921&RS=PN/83,53,921 Written by Amal Ahmed; edited by Jaya Anand.

*** Medtronic Vascular Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Medtronic Vascular, Santa Rosa, Calif., has been assigned a patent (8,353,892) developed by Dustin Thompson, Santa Rosa, Calif., and Patrick Macaulay, Santa Rosa, Calif., for "devices and methods for controlled-depth injection." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Devices and methods for simultaneous injection or delivery of two or more substances from separate syringes. The syringes are loaded into a device that has a handle and a screw driven mechanism for simultaneously depressing the plungers of the syringes. The user grasps the handle and positions the device. Thereafter, the screw mechanism is used to simultaneously advance the plungers of the syringes thereby simultaneously expelling the substances from the syringes." The patent application was filed on May 4, 2011 (13/100,961). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,892.PN.&OS=PN/83,53,892&RS=PN/83,53,892 Written by Amal Ahmed; edited by Jaya Anand.

*** Warsaw Orthopedic Assigned Patent for Surgical Instrument for Distracting a Spinal Disc Space ALEXANDRIA, Va., Jan. 19 -- Warsaw Orthopedic, Warsaw, Ind., has been assigned a patent (8,353,909) developed by Gary Karlin Michelson, Venice, Calif., for a "surgical instrument for distracting a spinal disc space." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Apparatus and a method of inserting spinal implants is disclosed in which an intervertebral space is first distracted, a hollow sleeve having teeth at one end is then driven into the vertebrae adjacent that disc space. A drill is then passed through the hollow sleeve removing disc and bone in preparation for receiving the spinal implant which is then inserted through the sleeve. Apparatus and a method of inserting spinal implants is disclosed in which an intervertebral space is first distracted to restore the normal angular relationship of the vertebrae adjacent to that disc space. An extended outer sleeve having extended portions capable of maintaining the vertebrae distracted in their normal angular relationship is then driven into the vertebrae adjacent that disc space. A drill is then passed through the hollow sleeve removing disc and bone in preparation for receiving the spinal implant which is then inserted through the sleeve." The patent application was filed on April 25, 2006 (11/410,609). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,909.PN.&OS=PN/83,53,909&RS=PN/83,53,909 Written by Amal Ahmed; edited by Jaya Anand.

*** Novasys Medical Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Novasys Medical, Newark, Calif., has been assigned a patent (8,353,908) developed by Stuart D. Edwards, Corral De Tierra, Calif., and Simon W. H. Thomas, Danville, Calif., for a "treatment of tissue in sphincters, sinuses, and orifices." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention comprises a method and apparatus for treatment of a body part. More particularly, a method and apparatus for heat treatment of tissue using a catheter inserted into a body part is described along with means for positioning the catheter and means for positioning a set of electrodes relative to a tissue sample for treatment. Still more particularly, radio frequency energy at about 400 to 500 kilohertz is used to provide heat for the tissue treatment." The patent application was filed on Dec. 28, 2009 (12/648,249). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,908.PN.&OS=PN/83,53,908&RS=PN/83,53,908 Written by Amal Ahmed; edited by Jaya Anand.

*** CareFusion 2200 Assigned Patent ALEXANDRIA, Va., Jan. 19 -- CareFusion 2200, San Diego, has been assigned a patent (8,353,897) developed by Mark Doyle, Del Mar, Calif., and Jimmy C. Caputo, Carlsbad, Calif., for a surgical tool kit.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A tool kit for interchanging tools within an at least partially closed area is provided. The tool kit includes at least one tool, each tool being preferably provided within a tubular housing, and adapted to pivot out from the tool kit so that they can be attached to a receiving tool. The tool is designed to be returned to the tool kit after use, and if desired, switched with a different tool. In one embodiment, a surgical system permitting surgical tools to be interchanged within a patient's body is provided. A method of interchanging surgical tools within a patient's body is also provided." The patent application was filed on July 14, 2010 (12/792,618). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,897.PN.&OS=PN/83,53,897&RS=PN/83,53,897 Written by Amal Ahmed; edited by Jaya Anand.

*** Vibrynt Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Vibrynt, Redwood City, Calif., has been assigned a patent (8,353,925) developed by seven co-inventors for "devices and methods for treatment of obesity." The co-inventors are Joshua Makower, Los Altos, Calif., Theodore M. Bender, Oakland, Calif., Brian K. Shiu, Sunnyvale, Calif., Pablo G. Acosta, Newark, Calif., Shuji Uemura, San Francisco, Josef L. Friedmann, Boulder Creek, Calif., and Crystine Lee, Vallejo, Calif.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Methods, devices, tools and assemblies for treating a patient to effect weight loss. One method embodiment involves passing a device including an expandable member in a collapsed configuration and a buoyancy member through an opening in the skin of a patient and into the abdominal cavity of the patient, and anchoring at least a portion of the expandable member, relative to at least one structure in the abdominal cavity. Devices including at least one expandable member and at least one buoyancy member are provided." The patent application was filed on June 23, 2008 (12/214,950). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,925.PN.&OS=PN/83,53,925&RS=PN/83,53,925 Written by Amal Ahmed; edited by Jaya Anand.

*** Revascular Therapeutics Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Revascular Therapeutics, Sunnyvale, Calif., has been assigned a patent (8,353,922) developed by Gerardo V. Noriega, Mountain View, Calif., Victor Chechelski, Winterville, N.C., and Sudaria Rudolfo, Union City, Calif., for a "guidewire for crossing occlusions or stenoses." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Systems and methods for crossing stenosis, partial occlusions, or complete occlusions within a body lumen. The systems generally include an elongate member such as a hollow guidewire that houses a rotatable and translatable drive shaft. The drive shaft typically has a distal portion that is advanced to create a path in the occlusive material that is large enough to allow the hollow guidewire to cross the occlusive material." The patent application was filed on Sept. 23, 2011 (13/241,628). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,922.PN.&OS=PN/83,53,922&RS=PN/83,53,922 Written by Amal Ahmed; edited by Jaya Anand.

*** Boston Scientific Scimed Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Boston Scientific Scimed, Maple Grove, Minn., has been assigned a patent (8,353,900) developed by six co-inventors for a "miniature circular mapping catheter." The co-inventors are Eugene Jung, Nesconset, N.Y., Dong Ik Shin, Poway, Calif., Eric Scott Vaughan, Washington, James Savage, San Diego, Robert C. Pacheco, Bayside, N.Y., and Jaime Merino, Elmont, N.Y.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "An ablation device, including a catheter and an ablation element incorporating one or more balloons at the distal end of the catheter, has a continuous passageway extending through it from the proximal end of the catheter to the distal side of the expandable ablation element. The ablation device ablates tissue by subjecting it to ultrasound energy, cryogenic energy, chemical, laser beam, microwave, or radiation energy. A probe carrying electrodes is introduced through this passageway and deploys, under the influence of its own resilience, to a structure incorporating a loop which is automatically aligned with the axis of the expandable ablation device, so that minimal manipulation is required to place the probe. Pulmonary vein potential is monitored in real time via the electrodes. The probe may have an atraumatic tip with a ball formed at the leading edge. The atraumatic tip prevents any tissue damage such as perforation of heart wall." The patent application was filed on July 11, 2008 (12/218,191). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,900.PN.&OS=PN/83,53,900&RS=PN/83,53,900 Written by Amal Ahmed; edited by Jaya Anand.

*** Cordis Assigned Patent ALEXANDRIA, Va., Jan. 19 -- Cordis, Miami Lakes, Fla., has been assigned a patent (8,353,926) developed by James H. Silver, Palo Alto, Calif., for a "long-term retrievable medical filter." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A medical filter has more than one pair of struts extending along an undulating path between a first and second end, which cooperate to define a first and second filter element having a plurality of cells, connected by a central portion with longitudinal strut sections. The struts extend between the first and second ends, and the struts tend to resiliently expand in radially outward directions from a compressed initial shape to an expanded deployed shape. In the expanded shape, the undulating path is defined by (i) a first portion of each pair of ribs extends substantially adjacent to each other for a distance from the first end, (ii) a second portion of each pair of ribs extends substantially adjacent to each other for a distance from the second end; and (iii) an intermediate portion of each one of a pair of ribs extends to curve away from each other." The patent application was filed on April 15, 2005 (10/592,910). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,53,926.PN.&OS=PN/83,53,926&RS=PN/83,53,926 Written by Amal Ahmed; edited by Jaya Anand.

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