U.S. Patents Awarded to Inventors in Maryland (Feb. 16)

(Targeted News Service Via Acquire Media NewsEdge) Targeted News Service Targeted News Service ALEXANDRIA, Va., Feb. 16 -- The following federal patents were awarded to inventors in Maryland.

*** Qiagen Gaithersburg, Jungheim Assigned Patent ALEXANDRIA, Va., Feb. 16 -- Qiagen Gaithersburg, Gaithersburg, Md., and Bert Jungheim, Boyds, Md., has been assigned a patent (8,372,359) developed by Bert Jungheim, and Andrew Leonard, Sykesville, Md., for a sample vial retainer.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A vial retainer system for an automated processing apparatus. The vial retainer system includes a track mounted to the processing apparatus, a rack adapted to slide in a longitudinal direction on the track, and a vial retainer positioned over the rack. The rack is movable in a distal direction to install the rack on the processing apparatus, and in a proximal direction, opposite the distal direction, to remove the rack from the processing apparatus. The rack is adapted to hold one or more vials in an upright orientation. The vial retainer has one or more a sloped surfaces inclined such that a distal end of each sloped surface is closer to the track than a proximal end of each sloped surface." The patent application was filed on Nov. 19, 2009 (12/622,140). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,372,359&OS=8,372,359&RS=8,372,359 Written by Arpi Sharma; edited by Anand Kumar.

*** U.S. Army Assigned Patent ALEXANDRIA, Va., Feb. 16 -- The U.S. Army has been assigned a patent (8,373,107) developed by Ronald Everett Meyers, Columbia, Md., and Keith Scott Deacon, Columbia, Md., for a "method and apparatus for non-line-of-sight imaging of a first area using photons detected from a second area." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A system for imaging information comprising a spatial receiver, a chaotic photon light source comprising a first beam directed at a first predetermined area containing an object, and a second beam received by the spatial receiver and measured at specific intervals in time; the spatial receiver transmitting spatial information correlated to specific intervals of time to a processor; and a first receiver detecting the influence of the object on the first light beam; the first receiver not being in the line of sight with the first predetermined area and adapted to detect light from a second predetermined area spaced from the first predetermined area, the at least one processor operating to correlate the outputs of the first receiver with spatial information derived from the spatial receiver at correlating intervals of time to create an image of the object and a method for practicing the invention." The patent application was filed on Aug. 4, 2011 (13/198,133). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,373,107&OS=8,373,107&RS=8,373,107 Written by Arpi Sharma; edited by Anand Kumar.

*** Genentech Assigned Patent ALEXANDRIA, Va., Feb. 16 -- Genentech, South San Francisco, Calif., has been assigned a patent (8,372,404) developed by four co-inventors for an "anti-C5/C5a antibodies and methods of use." The co-inventors are Michael Fung, Gaithersburg, Md., Meisheng Lu, Houston, William N.C. Sun, Shanghai, China, and Cecily R.Y. Sun, Shanghai, China.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention relates to inhibitors that bind to C5 and C5a, but which do not prevent the activation of C5 and do not prevent formation of or inhibit the activity of C5b. One example of such an inhibitor molecule is the monoclonal antibody designated MAb137-26, which binds to a shared epitope of human C5 and C5a. These inhibitors may be used to inhibit the activity of C5a in treating diseases and conditions mediated by excessive or uncontrolled production of C5a. The inhibitor molecules are also useful for diagnostic detection of the presence/absence or amount of C5 or C5a." The patent application was filed on May 29, 2012 (13/482,328). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,372,404&OS=8,372,404&RS=8,372,404 Written by Arpi Sharma; edited by Anand Kumar.

*** U.S. Navy Assigned Patent ALEXANDRIA, Va., Feb. 16 -- The U.S. Navy has been assigned a patent (8,373,141) developed by four co-inventors for "photographing and measuring a territorial radiation field." The co-inventors are Garry E. Shields, Ashburn, Va., Paul W. Brown, Columbia, Md., Gordon K. Riel, Edgewater, Md., and Robert D. Rogalski, Annapolis, Md.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "Dosimeter chips are widely distributed over a territorial area. This is followed by photographing the area from above to produce a color photograph. The color photograph is compared with radiation/color calibration data for the dosimeter chips. The total radiation accumulation is determined from the calibration data. The invention is for emergency use after civil accidents, for ascertaining a threat to military personnel before entering the battlefield or for interrogating a ship at sea." The patent application was filed on Sept. 28, 2009 (12/567,814). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,373,141&OS=8,373,141&RS=8,373,141 Written by Arpi Sharma; edited by Anand Kumar.

*** University of Florida Research Foundation Assigned Patent ALEXANDRIA, Va., Feb. 16 -- The University of Florida Research Foundation, Gainesville, Fla., has been assigned a patent (8,372,409) developed by Mansour Mohamadzadeh, Frederick, Md., for a "dendritic cell binding proteins and uses thereof." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides novel peptides which specifically targets and binds to dendritic cells. Also provided are fusion compositions comprising these peptides and a non-dendritic protein of fragments thereof. Further provided are DNA sequences encoding these peptides and fusion compositions. Methods of using the peptides or fusion compositions to promote an immune responses in an individual via administration also are provided." The patent application was filed on April 8, 2004 (10/552,153). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,372,409&OS=8,372,409&RS=8,372,409 Written by Arpi Sharma; edited by Anand Kumar.

*** Genentech Assigned Patent for Humanized Anti-factor D Antibodies and Uses ALEXANDRIA, Va., Feb. 16 -- Genentech, South San Francisco, Calif., has been assigned a patent (8,372,403) developed by six co-inventors for a "humanized anti-factor D antibodies and uses thereof." The co-inventors are Ling-Ling An, Boyds, Md., Sek Chung Fung, Gaithersburg, Md., Robert F. Kelley, San Bruno, Calif., Henry B. Lowman, El Granada, Calif., Sanjaya Singh, Sandy Hook, Conn., and Herren Wu, Boyds, Md.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease." The patent application was filed on May 1, 2012 (13/461,253). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,372,403&OS=8,372,403&RS=8,372,403 Written by Arpi Sharma; edited by Anand Kumar.

*** U.S. Army Assigned Patent ALEXANDRIA, Va., Feb. 16 -- The U.S. Army has been assigned a patent (8,372,197) developed by Stefan P. Svensson, Columbia, Md., for a "substrate temperature accuracy and temperature control flexibility in a molecular beam epitaxy system." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A control system and method for controlling temperatures while performing a MBE deposition process, wherein the control system comprises a MBE growth structure; a heater adapted to provide heat for the MBE deposition process on the MBE growth structure; and a control computer adapted to receive a plurality of dynamic feedback control signals derived from the MBE growth structure; switch among a plurality of control modes corresponding with the plurality of dynamic feedback control signals; and send an output power signal to the heater to control the heating for the MBE deposition process based on a combination of the plurality of control modes. In one embodiment, the plurality of dynamic feedback control signals comprises thermocouple signals and pyrometer signals." The patent application was filed on Aug. 29, 2011 (13/219,762). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,72,197.PN.&OS=PN/83,72,197&RS=PN/83,72,197 Written by Amal Ahmed; edited by Jaya Anand.

*** Biomet Manufacturing Assigned Patent ALEXANDRIA, Va., Feb. 16 -- Biomet Manufacturing, Warsaw, Ind., has been assigned a patent (8,372,154) developed by six co-inventors for a "method and apparatus for wrist arthroplasty." The co-inventors are Jason M. Schultz, Hamilton, Ohio, Andrew K. Palmer, East Syracuse, N.Y., Kevin T. Stone, Winona Lake, Ind., Thomas J. Graham, Cockeysville, Md., Brian K. Berelsman, Warsaw, Ind., and James W. Strickland, Zionsville, Ind.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A prosthetic wrist having at least one of a radial insert, which is configured to be fixed to a radius of a patient, a carpal implant or a wrist bearing component. The carpal implant can include a body and a pair of flanges, each of which being skewed to the axis of the body in a manner that permits them to abut the ulnar side of the hamate bone and the radial side of the distal portion of the carpal bone complex, respectively. The radial insert may be provided with a plurality of modular portions to allow for selection and customization of an implant. Also the various portions can allow for a hemi- or total, or revision wrist arthroplasty. The modular portions can allow for intraopertative customization." The patent application was filed on Oct. 27, 2005 (11/260,729). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,72,154.PN.&OS=PN/83,72,154&RS=PN/83,72,154 Written by Amal Ahmed; edited by Jaya Anand.

*** Algenol Biofuels Assigned Patent ALEXANDRIA, Va., Feb. 16 -- Algenol Biofuels, Bonita Springs, Fla., has been assigned a patent (8,372,613) developed by Pengcheng Patrick Fu, Honolulu, and Jason Dexter, Baltimore, for "methods and compositions for ethanol producing cyanobacteria." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention relates to methods and systems for the production of ethanol by cyanobacteria. More specifically, the methods can be used to produce ethanol using genetically engineered light responsive cyanobacteria." The patent application was filed on Jan. 16, 2007 (12/160,770). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,372,613.PN.&OS=PN/8,372,613&RS=PN/8,372,613 Written by Kusum Sangma; edited by Anand Kumar.

*** Life Technologies Assigned Patent ALEXANDRIA, Va., Feb. 16 -- Life Technologies, Carlsbad, Calif., has been assigned a patent (8,372,604) developed by Jun Lee, San Diego, and Ayoub Rashtchian, Gaithersburg, Md., for "compositions and methods for reverse transcriptase-polymerase chain reaction (RT-PCR)." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention is directed to compositions and methods useful for the amplification of nucleic acid molecules by reverse transcriptase-polymerase chain reaction (RT-PCR). Specifically, the invention provides compositions and methods for the amplification of nucleic acid molecules in a simplified one- or two-step RT-PCR procedure using combinations of reverse transcriptase and thermostable DNA polymerase enzymes in conjunction with sulfur-containing molecules or acetate-containing molecules (or combinations of such sulfur-containing molecules and acetate-containing molecules), and optionally bovine serum albumin. The invention thus facilitates the rapid and efficient amplification of nucleic acid molecules and the detection and quantitation of RNA molecules. The invention also is useful in the rapid production and amplification of cDNAs which may be used for a variety of industrial, medical and forensic purposes." The patent application was filed on Dec. 29, 2010 (12/981,240). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,372,604.PN.&OS=PN/8,372,604&RS=PN/8,372,604 Written by Kusum Sangma; edited by Anand Kumar.

*** Adlyfe Assigned Patent ALEXANDRIA, Va., Feb. 16 -- Adlyfe, Rockville, Md., has been assigned a patent (8,372,593) developed by Cindy S. Orser, Lafayette, Colo., Tao Pan, Gaithersburg, Md., and Jasmeet Sethi, Germantown, Md., for a "method for detecting misfolded proteins and prions." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention provides methods and kits for detecting conformationally altered proteins, such as prions or other proteins associated with disease states, in a sample. The methods comprise selectively capturing and separating complexes of peptide and conformationally altered protein from substances that interfere with detection of such complexes, and preferably amplification of the detection signal b addition of a second double-labeled peptide." The patent application was filed on Feb. 14, 2006 (11/884,316). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,372,593.PN.&OS=PN/8,372,593&RS=PN/8,372,593 Written by Kusum Sangma; edited by Anand Kumar.

*** Becton, Dickinson and Co. Assigned Patent ALEXANDRIA, Va., Feb. 16 -- Becton, Dickinson and Co., Franklin Lakes, N.J., has been assigned a patent (8,372,605) developed by eight co-inventors for an immuno-amplification. The co-inventors are James Nadeau, Ellicott City, Md., Tobin J. Hellyer, Westminster, Md., Dolores M. Berger, Baltimore, William Nussbaumer, Baltimore, Robert Rosenstein, Ellicott City, Md., Andrew Kuhn, Baltimore, Sha-Sha Wang, Wellesley, Mass., and Keith Edward Thornton, Owings Mill, Md.

The abstract of the patent published by the U.S. Patent and Trademark Office states: "A high-sensitivity, low-background immuno-amplification assay is provided, which offers a streamlined workflow suitable for high-throughput assays of clinically relevant samples, such as blood and other bodily fluids. The assay comprises the use of two proximity members that each comprise an analyte-specific binding component conjugated to an oligonucleotide. Binding an analyte brings the oligonucleotide moieties of the proximity members in sufficiently close contact that the oligonucleotides form an amplicon. The presence of the analyte then is detected through amplification of the amplicon and detection of the amplified nucleic acids. The sensitivity of the assay of the present invention is improved by preventing spurious or non-specific amplicon formation by proximity members that are not complexed with an analyte." The patent application was filed on March 25, 2011 (13/072,314). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,372,605.PN.&OS=PN/8,372,605&RS=PN/8,372,605 Written by Kusum Sangma; edited by Anand Kumar.

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