[March 06, 2013]

InSite Vision Announces Date for Annual Shareholder Meeting

InSite Vision Incorporated (OTCBB: INSV), a company developing ophthalmic products for unmet eye care needs, today announced that the company's Annual Meeting of Stockholders will be held at 10:00 a.m. Pacific Time on Wednesday, May 29, 2013, for shareholders of record on April 3, 2013. The Annual Meeting will be held at InSite Vision's headquarters at 965 Atlantic Avenue, Alameda, California. InSite Vision plans to mail the definitive proxy statement for the Annual Meeting, as well as its annual report, in April.

About InSite Vision

InSite Vision is advancing new ophthalmologic products for unmet eye care needs based on its innovative DuraSite^® platform technologies. The DuraSite and DuraSite 2 drug delivery systes extend the duration of drug retention on the surface of the eye, thereby reducing the frequency of treatment and improving the efficacy of topical drugs.

The DuraSite platform is currently leveraged in two commercial products for the treatment of bacterial eye infections, AzaSite^® (azithromycin ophthalmic solution) 1%, marketed in the U.S. by Merck, and Besivance^® (besifloxacin ophthalmic suspension) 0.6%, marketed by Bausch + Lomb. InSite Vision is also advancing three novel ophthalmic therapeutics through Phase 3 clinical studies: AzaSite Plus^™ and DexaSite^™ for the treatment of eye infections, and BromSite^™ for pain and inflammation associated with ocular surgery. For further information on InSite Vision, please visit www.insitevision.com.

AzaSite^®, DuraSite^® and DuraSite 2^® are registered trademarks of InSite Vision Incorporated.

AzaSite Plus^™, BromSite^™ and DexaSite^™ are trademarks of InSite Vision Incorporated.

BESIVANCE^® is a registered trademark of Bausch + Lomb Incorporated.

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