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U.S. Patents Awarded to Inventors in California (March 16)(Targeted News Service Via Acquire Media NewsEdge) Targeted News Service Targeted News Service ALEXANDRIA, Va., March 16 -- The following federal patents were awarded to inventors in California. *** Stanford University, Honda Motor Assigned Patent ALEXANDRIA, Va., March 16 -- Stanford University, Palo Alto, Calif., and Honda Motor, Tokyo, have been assigned a patent (8,394,550) developed by fie co-inventors for a "nano-patterned electrolytes in solid oxide fuel cells." The co-inventors are Cheng-Chieh Chao, Stanford, Calif., Yi Cui, Stanford, Calif., Ching-Mei Hsu, Stanford, Calif., Young Beom Kim, Stanford, Calif., and Friedrich B. Prinz, Woodside, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "A nano-patterned membrane electrode assembly (MEA) is provided, which includes an electrolyte membrane layer having a three-dimensional close-packed array of hexagonal-pyramids, a first porous electrode layer, disposed on a top surface of the electrolyte membrane layer that conforms to a top surface-shape of the three-dimensional close-packed array of hexagonal-pyramids, and a second porous electrode layer disposed on a bottom surface of said electrolyte membrane layer that conforms to a bottom surface-shape of the three-dimensional close-packed array of hexagonal-pyramids, where a freestanding nano-patterned MEA is provided." The patent application was filed on Sept. 14, 2010 (12/807,777). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,550.PN.&OS=PN/8,394,550&RS=PN/8,394,550 Written by Kusum Sangma; edited by Anand Kumar. *** Applied Materials Assigned Patent ALEXANDRIA, Va., March 16 -- Applied Materials, Santa Clara, Calif., has been assigned a patent (8,394,196) developed by Yihwan Kim, Milpitas, Calif., for a "formation of in-situ phosphorus doped epitaxial layer containing silicon and carbon." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Methods for formation epitaxial layers containing silicon and carbon doped with phosphorus are disclosed. The pressure is maintained equal to or above 100 torr during deposition. The methods result in the formation of a film including substitutional carbon. Specific embodiments pertain to the formation and treatment of epitaxial layers in semiconductor devices, for example, Metal Oxide Semiconductor Field Effect Transistor (MOSFET) devices." The patent application was filed on Dec. 12, 2006 (11/609,826). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,196.PN.&OS=PN/83,94,196&RS=PN/83,94,196 Written by Amal Ahmed; edited by Jaya Anand. *** Life Technologies Assigned Patent ALEXANDRIA, Va., March 16 -- Life Technologies, Carlsbad, Calif., has been assigned a patent (8,394,585) developed by Shoulian Dong, Mountain View, Calif., and Junko Stevens, Menlo Park, Calif., for a "DNA methylation detection methods." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present teachings provide DNA methylation quantification methods that avoid bisulfite treatment of DNA. Methylation-specific binding proteins (MeDNA binding proteins) and non-methylation specific binding proteins (non-MeDNA binding proteins) are employed in various embodiments to modulate the accessibility of nucleic acids to primer extension reactions. After selectively removing the target nucleic acids, the extension products can be analyzed and methylation quantitated. In some embodiments, the analysis comprises real-time PCR." The patent application was filed on July 11, 2011 (13/180,382). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,585.PN.&OS=PN/8,394,585&RS=PN/8,394,585 Written by Kusum Sangma; edited by Anand Kumar. *** Sub-One Technology Assigned Patent ALEXANDRIA, Va., March 16 -- Sub-One Technology, Pleasanton, Calif., has been assigned a patent (8,394,197) developed by five co-inventors for a "corrosion-resistant internal coating method using a germanium-containing precursor and hollow cathode techniques." The co-inventors are Andrew W. Tudhope, Danville, Calif., Thomas B. Casserly, San Ramon, Calif., Karthik Boinapally, Fremont, Calif., Deepak Upadhyaya, Fremont, Calif., and William J. Boardman, Danville, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Enhanced corrosion resistance is achieved in a coating by using a germanium-containing precursor and hollow cathode techniques to form a first layer directly on the surface of a workpiece, prior to forming an outer layer, such as a layer of diamond-like carbon (DLC). The use of a germanium or germanium-carbide precursor reduces film stress and enables an increase in the thickness of the subsequently formed DLC. Germanium incorporation also reduces the porosity of the layer. In one embodiment, a cap layer containing germanium is added after the DLC in order to further reduce the susceptibility of the coating to chemical penetration from the top." The patent application was filed on July 11, 2008 (12/218,119). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,197.PN.&OS=PN/83,94,197&RS=PN/83,94,197 Written by Amal Ahmed; edited by Jaya Anand. *** Genentech Assigned Patent ALEXANDRIA, Va., March 16 -- Genentech, South San Francisco, Calif., has been assigned a patent (8,394,607) developed by five co-inventors for an "anti-CD22 antibodies and immunoconjugates and methods of use." The co-inventors are Allen J. Ebens Jr., San Carlos, Calif., Alane M. Gray, Brisbane, Calif., Wei-Ching Liang, Foster City, Calif., Yan Wu, Foster City, Calif., and Shang-Fan Yu, Milpitas, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Anti-CD22 antibodies and immunoconjugates thereof are provided. Methods of using anti-CD22 antibodies and immunoconjugates thereof are provided." The patent application was filed on July 26, 2012 (13/559,464). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,607.PN.&OS=PN/8,394,607&RS=PN/8,394,607 Written by Kusum Sangma; edited by Anand Kumar. *** Deeya Energy Assigned Patent ALEXANDRIA, Va., March 16 -- Deeya Energy, Fremont, Calif., has been assigned a patent (8,394,529) developed by Majid Keshavarz, Pleasanton, Calif., and Aravamuthan Varadarajan, Fremont, Calif., for a "preparation of flow cell battery electrolytes from raw materials." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A method for preparing a redox flow battery electrolyte is provided. In some embodiments, the method includes the processing of raw materials that include sources of chromium ions and/or iron ions. The method further comprises the removal of impurities such as metal ions from those raw materials. In some embodiments, an ammonium salt may be used to remove metal impurities from an aqueous mixture of chromium ions and/or iron ions. Further provided is a redox flow battery comprising at least one electrolyte prepared from the above-identified methods." The patent application was filed on May 28, 2010 (12/790,595). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,529.PN.&OS=PN/8,394,529&RS=PN/8,394,529 Written by Kusum Sangma; edited by Anand Kumar. *** Global Energy Science Assigned Patent ALEXANDRIA, Va., March 16 -- Global Energy Science, Santa Barbara, Calif., has been assigned a patent (8,394,518) developed by Halbert Fischel, Santa Barbara, Calif., and Sheldon L. Epstein, Wilmette, Ill., for a "galvanic electrochemical cells for generating alternating current electricity." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Galvanic electrochemical cells (100, 300, 700, 900) for converting chemical energy into electrical energy, such as batteries, flow cells and fuel cells with a cylindrical rotating filter (120.sub.X, 326, 726, 910) having ion-porous (120.sub.P, 326.sub.P, 726.sub.P, 910.sub.P) and ion-non-porous filter (120.sub.N, 326.sub.N, 726.sub.N, 910.sub.N) for use with both thixotropic and non-conducting electrolytes that generates fluid flows in electrolytes between static cylindrical current collector segments (106, 304.sub.X, 306.sub.X, 710.sub.X, 902.sub.X; 108, 314.sub.X, 316.sub.X, 712.sub.X, 906) and the filter (120, 326, 726, 910) are disclosed that generate electric currents varying in amplitude that can be converted into alternating current electricity." The patent application was filed on April 2, 2012 (13/437,771). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,518.PN.&OS=PN/8,394,518&RS=PN/8,394,518 Written by Kusum Sangma; edited by Anand Kumar. *** Advanced Cardiovascular Systems Assigned Patent ALEXANDRIA, Va., March 16 -- Advanced Cardiovascular Systems, Santa Clara, Calif., has been assigned a patent (8,394,447) developed by Grayson Morris, San Francisco, Svava Maria Atladottir, Mountain View, Calif., and Carla Pienknagura, San Carlos, Calif., for an "abluminal stent coating apparatus and method using a brush assembly." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The apparatus and method use an optical feedback system to align a brush assembly with a stent strut. Once alignment is achieved, a coating is dispensed onto the stent strut via the brush assembly and the brush assembly is moved along the stent strut to coat the stent strut." The patent application was filed on July 27, 2009 (12/510,121). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,447.PN.&OS=PN/8,394,447&RS=PN/8,394,447 Written by Kusum Sangma; edited by Anand Kumar. *** Abbott Cardiovascular Systems Assigned Patent ALEXANDRIA, Va., March 16 -- Abbott Cardiovascular Systems, Santa Clara, Calif., has been assigned a patent (8,394,446) developed by Ni Ding, San Jose, Calif., for "methods of providing antioxidants to implantable medical devices." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Methods of incorporating an antioxidant into a medical device including a polymer are described, and methods of packaging medical devices." The patent application was filed on June 16, 2009 (12/485,756). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,446.PN.&OS=PN/8,394,446&RS=PN/8,394,446 Written by Kusum Sangma; edited by Anand Kumar. *** Medtronic MiniMed Assigned Patent ALEXANDRIA, Va., March 16 -- Medtronic MiniMed, Northridge, Calif., has been assigned a patent (8,394,463) developed by nine co-inventors for a "crosslinking compounds at negative pressures and materials made by such methods." The co-inventors are Chia-Hung Chiu, Granada Hills, Calif., Marco Sillus, Porter Ranch, Calif., Barry Pham, Los Angeles, Ly Phou, Los Angeles, Gil Bruso, Simi Valley, Calif., Christopher R. Enegren, Moorpark, Calif., Heath Jensen, Los Angeles, Michael Paul Minor, Castaic, Calif., and Rajiv Shah, Rancho Palos Verdes, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Embodiments of the invention provide methods of crosslinking various compounds and materials made by these methods. Materials made by embodiments of the invention include glucose sensors used in the management of diabetes." The patent application was filed on Jan. 22, 2010 (12/692,001). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,463.PN.&OS=PN/8,394,463&RS=PN/8,394,463 Written by Kusum Sangma; edited by Anand Kumar. *** Stanford University Assigned Patent ALEXANDRIA, Va., March 16 -- Stanford University, Palo Alto, Calif., has been assigned a patent (8,394,599) developed by Omar D. Perez, San Francisco, Garry P. Nolan, San Francisco, and Jonathan M. Irish, Palo Alto, Calif., for "methods and compositions for risk stratification." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of potentiators of cellular activation allows for characterization of such pathways and cell populations." The patent application was filed on May 12, 2010 (12/778,847). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,599.PN.&OS=PN/8,394,599&RS=PN/8,394,599 Written by Kusum Sangma; edited by Anand Kumar. *** California Institute of Technology, University of California Assigned Patent ALEXANDRIA, Va., March 16 -- California Institute of Technology, Pasadena, Calif., and the University of California, Oakland, Calif., have been assigned a patent (8,394,590) developed by five co-inventors for a "capture agents and related methods and systems for detecting and/or sorting targets." The co-inventors are Gabriel A. Kwong, Alhambra, Calif., Caius G. Radu, Los Angeles, Owen Witte, Sherman Oaks, Calif., James R. Heath, South Pasadena, Calif., and Antoni Ribas, Los Angeles. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Polynucleotide-encoded capture agents for target detection and in particular modular polynucleotide-capture agents comprising a target binding component, a scaffold component and an encoding component formed by standardized molecular units that can be coupled and decoupled in a controlled fashion, and related compositions methods and systems." The patent application was filed on Oct. 8, 2010 (12/901,151). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,590.PN.&OS=PN/8,394,590&RS=PN/8,394,590 Written by Kusum Sangma; edited by Anand Kumar. *** Envia Systems Assigned Patent ALEXANDRIA, Va., March 16 -- Envia Systems, Newark, Calif., has been assigned a patent (8,394,534) developed by four co-inventors for a "layer-layer lithium rich complex metal oxides with high specific capacity and excellent cycling." The co-inventors are Herman A. Lopez, Sunnyvale, Calif., Subramanian Venkatachalam, Pleasanton, Calif., Deepak Kumaar Kandasamy Karthikeyan, Foster City, Calif., and Sujeet Kumar, Newark, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Lithium rich and manganese rich lithium metal oxides are described that provide for excellent performance in lithium-based batteries. The specific compositions can be engineered within a specified range of compositions to provide desired performance characteristics. Selected compositions can provide high values of specific capacity with a reasonably high average voltage. Compositions of particular interest can be represented by the formula, xLi.sub.2MnO.sub.3.(1-x)LiNi.sub.u+.DELTA.Mn.sub.u-.DELTA.Co.sub.wA.sub.y- O.sub.2. The compositions undergo significant first cycle irreversible changes, but the compositions cycle stably after the first cycle." The patent application was filed on Aug. 27, 2010 (12/869,976). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,534.PN.&OS=PN/8,394,534&RS=PN/8,394,534 Written by Kusum Sangma; edited by Anand Kumar. *** Phoenix Biotechnology Assigned Patent ALEXANDRIA, Va., March 16 -- Phoenix Biotechnology, San Antonio, has been assigned a patent (8,394,434) developed by Otis Crandell Addington, San Antonio, Feng Zhang, Burlingame, Calif., and John J. Koleng, Austin, Texas, for an "SCF extract containing cardiac glycoside." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A supercritical fluid (SCF) extract of a cardiac glycoside-containing plant mass is provided. The extract can be included in a pharmaceutical composition containing an extract-solubilizing amount of solubilizer. Oleandrin is included within the extract when a cardiac glycoside-containing plant, such as Nerium oleander, is extracted by SCF extraction. The extract can also contain one or more other SCF extractable pharmacologically active agents. The composition can be used to treat a wide range of disorders that are therapeutically responsive to a cardiac glycoside." The patent application was filed on March 12, 2012 (13/417,686). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,434.PN.&OS=PN/8,394,434&RS=PN/8,394,434 Written by Kusum Sangma; edited by Anand Kumar. *** Scripps Research Institute Assigned Patent ALEXANDRIA, Va., March 16 -- Scripps Research Institute, La Jolla, Calif., has been assigned a patent (8,394,605) developed by Jiangyun Wang, Beijing, and Peter G. Schultz, La Jolla, Calif., for a "genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetase that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel sythetases molecules, methods for identifying and making the novel synthetases, methods for producing containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lapidated proteins) through targeted modification of the phenylselenocysteine residue in a protein." The patent application was filed on June 8, 2012 (13/492,240). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,605.PN.&OS=PN/8,394,605&RS=PN/8,394,605 Written by Kusum Sangma; edited by Anand Kumar. *** University of Texas System, Chevron USA Assigned Patent ALEXANDRIA, Va., March 16 -- The University of Texas System, Austin, Texas, and Chevron USA, San Ramon, Calif., have been assigned a patent (8,394,182) developed by five co-inventors for a "crosslinked membrane and polymer for making same and method of using membrane." The co-inventors are William J. Koros, Atlanta, David Wallace, Smyrna, Ga., John Wind, Berkeley, Calif., Claudia Staudt-Bickel, Heidelberg, Germany, and Stephen J. Miller, San Francisco. The abstract of the patent published by the U.S. Patent and Trademark Office states: "A composition of and a method of making high performance crosslinked membranes are described. The membranes have a high resistance to plasticization by use of crosslinking. The preferred polymer material for the membrane is a polyimide polymer comprising covalently bonded ester crosslinks. The resultant membrane exhibits a high permeability of CO.sub.2 in combination with a high CO.sub.2/CH.sub.4selectivity. Another embodiment provides a method of making the membrane from a monesterified polymer followed by final crosslinking after the membrane is formed." The patent application was filed on Dec. 17, 2010 (12/972,301). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,182.PN.&OS=PN/83,94,182&RS=PN/83,94,182 Written by Amal Ahmed; edited by Jaya Anand. *** StemBios Technologies Assigned Patent ALEXANDRIA, Va., March 16 -- StemBios Technologies, Monterey Park, Calif., has been assigned a patent (8,394,630) developed by James Wang, Monterey Park, Calif., and Yun Yen, Arcadia, Calif., for "producing a mammalian pluripotent cell population from mammalian blastomere-like stem cells (BLSCs)." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Disclosed are novel stem cells of non-embryonic origins and the uses thereof." The patent application was filed on Jan. 13, 2010 (12/686,584). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=8,394,630.PN.&OS=PN/8,394,630&RS=PN/8,394,630 Written by Kusum Sangma; edited by Anand Kumar. *** Roche Diagnostics Operations Assigned Patent ALEXANDRIA, Va., March 16 -- Roche Diagnostics Operations, Indianapolis, has been assigned a patent (8,394,343) developed by four co-inventors for an "integrated test strip container with retaining insert." The co-inventors are Frank A. Chan, Sunnyvale, Calif., Matthew C. Sauers, Indianapolis, Abner D. Joseph, Carmel, Ind., and Christopher Wiegel, Sunnyvale, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "A blood glucose meter for providing easy access to test strips and measuring blood glucose, a disposable and removable cartridge for providing easy access to test strips, and methods of manufacturing and utilization thereof are disclosed. The blood glucose meter for providing easy access to test strips and measuring blood glucose has a disposable and removable cartridge, a retaining member which releasably retains the test strips in a stacked configuration, and a housing. The disposable and removable cartridge has a rigid lid attached to a flexible body." The patent application was filed on April 27, 2010 (12/768,036). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,343&OS=8,394,343&RS=8,394,343 Written by Arpi Sharma; edited by Anand Kumar. *** RTI Biologics Assigned Patent ALEXANDRIA, Va., March 16 -- RTI Biologics, Dover, Del., has been assigned a patent (8,394,141) developed by six co-inventors for "connective-tissue-based or dermal-tissue-based grafts/implants." The co-inventors are C. Randal Mills, Tioga, Fla., John R. Bianchi, Gainesville, Fla., Michael R. Roberts, Gainesville, Fla., David T. Cheung, Arcadia, Calif., Chandrasekaran Nataraj, Gainesville, Fla., and John W. Howell, Gainesville, Fla. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell." The patent application was filed on Sept. 9, 2010 (12/807,599). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,141.PN.&OS=PN/83,94,141&RS=PN/83,94,141 Written by Amal Ahmed; edited by Jaya Anand. *** AccessClosure Assigned Patent ALEXANDRIA, Va., March 16 -- AccessClosure, Mountain View, Calif., has been assigned a patent (8,394,122) developed by Celso J. Bagaoisan, Union City, Calif., Juan Domingo, Union City, Calif., and Sieu Duong, San Francisco, for an "apparatus and methods for sealing a vascular puncture." The abstract of the patent published by the U.S. Patent and Trademark Office states: "An apparatus for sealing a puncture includes a cartridge, a pusher member, a sealant, and a tamping device on a proximal end of the cartridge. During use, the cartridge, sealant, and pusher member are advanced over a positioning member and into the puncture by advancing a cartridge hub carrying the tamping device. When further distal advancement of the cartridge is limited, the cartridge hub is further advanced, activating the tamping device, and causing the pusher member to advance relative to the sealant to compress the sealant within the puncture." The patent application was filed on Nov. 12, 2009 (12/617,693). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,122.PN.&OS=PN/83,94,122&RS=PN/83,94,122 Written by Amal Ahmed; edited by Jaya Anand. *** Lawrence Livermore National Security Assigned Patent ALEXANDRIA, Va., March 16 -- Lawrence Livermore National Security, Livermore, Calif., has been assigned a patent (8,394,351) developed by four co-inventors for a "synthesis of triazole-based and imidazole-based zinc catalysts." The co-inventors are Carlos A. Valdez, San Ramon, Calif., Joe H. Satcher Jr., Patterson, Calif., Roger D. Aines, Livermore, Calif., and Sarah E. Baker, Pleasanton, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Various methods and structures of complexes and molecules are described herein related to a zinc-centered catalyst for removing carbon dioxide from atmospheric or aqueous environments. According to one embodiment, a method for creating a tris(triazolyl)pentaerythritol molecule includes contacting a pentaerythritol molecule with a propargyl halide molecule to create a trialkyne molecule, and contacting the trialkyne molecule with an azide molecule to create the tris(triazolyl)pentaerythritol molecule. In another embodiment, a method for creating a tris(imidazolyl)pentaerythritol molecule includes alkylating an imidazole 2-carbaldehyde molecule to create a monoalkylated aldehyde molecule, reducing the monoalkylated aldehyde molecule to create an alcohol molecule, converting the alcohol molecule to create an alkyl halide molecule using thionyl halide, and reacting the alkyl halide molecule with a pentaerythritol molecule to create a tris(imidazolyl)pentaerythritol molecule. In another embodiment, zinc is bound to the tris(triazolyl)pentaerythritol molecule to create a zinc-centered tris(triazolyl)pentaerythritol catalyst for removing carbon dioxide from atmospheric or aqueous environments." The patent application was filed on May 25, 2010 (12/787,356). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,351&OS=8,394,351&RS=8,394,351 Written by Arpi Sharma; edited by Anand Kumar. *** Natural Alternatives International Assigned Patent ALEXANDRIA, Va., March 16 -- Natural Alternatives International, San Marcos, Calif., has been assigned a patent (8,394,402) developed by Roger Harris, New Market, United Kingdom, and John Wise, San Marcos, Calif., for "compositions and methods for the sustained release of beta-alanine." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Methods and compositions are provided for increasing the anaerobic working capacity of muscle and other tissues. Also provided are compositions formulated for the sustained release of free beta-alanine. Also provided is a dietary supplement formulated, for example, as a solid food product, an edible suspension, liquid or semi-liquid as described herein." The patent application was filed on Oct. 5, 2012 (13/646,184). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,402&OS=8,394,402&RS=8,394,402 Written by Arpi Sharma; edited by Anand Kumar. *** Depomed Assigned Patent ALEXANDRIA, Va., March 16 -- Depomed, Newark, Calif., has been assigned a patent (8,394,408) developed by Chien-Hsuan Han, Sunnyvale, Calif., Sui Yuen Eddie Hou, Foster City, Calif., and Monica L. Reid, San Mateo, Calif., for a "gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Compositions and methods for the treatment of pain in a mammal are described. More specifically, a dosage form designed for release of acetaminophen and an opioid is described, wherein the dosage form provides delivery of the drugs to the upper gastrointestinal tract ("GI") of a mammal for an extended period of time." The patent application was filed on Jan. 27, 2012 (13/360,595). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,408&OS=8,394,408&RS=8,394,408 Written by Arpi Sharma; edited by Anand Kumar. *** Xencor Assigned Patent ALEXANDRIA, Va., March 16 -- Xencor, Monrovia, Calif., has been assigned a patent (8,394,374) developed by seven co-inventors for an "optimized antibodies that target HM1.24." The co-inventors are Matthew J. Bernett, Monrovia, Calif., John R. Desjarlais, Pasadena, Calif., Sher Bahadur Karki, Pomona, Calif., Gregory Alan Lazar, Arcadia, Calif., Umesh S. Muchhal, Monrovia, Calif., Duc-Hanh Thi Nguyen, Sylmar, Calif., and John O. Richards, Duarte, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present disclosure describes antibodies that target HM1.24. In various aspects, the antibodies have specific CDR, variable, or full length sequences, have modifications with the parent antibody, or include at least one one modification relative to a parent antibody that alters affinity to an Fc.gamma.R or alters effector function as compared to the parent antibody. Nucleic acids encoding the antibodies and methods of using the antibodies are also disclosed." The patent application was filed on Sept. 18, 2007 (12/441,885). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,374&OS=8,394,374&RS=8,394,374 Written by Arpi Sharma; edited by Anand Kumar. *** Smith & Nephew, University of Pennsylvania Assigned Patent ALEXANDRIA, Va., March 16 -- Smith & Nephew, Memphis, Tenn., and the University of Pennsylvania, Philadelphia, have been assigned a patent (8,394,148) developed by eight co-inventors for a "tibial component of high performance knee prosthesis." The co-inventors are Jason K. Otto, Plantation, Fla., Brian McKinnon, Bartlett, Tenn., Dean Hughes, Memphis, Tenn., Michael Ries, Tiberon, Calif., Jan Victor, Brugge, Belgium, Johan Bellemans, Langdorp, Belgium, Jonathan Garino, Villanova, Pa., and Timothy Wilton, Duffield, United Kingdom. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Knee prostheses featuring components that more faithfully replicate the structure and function of the human knee joint in order to provide, among other benefits: greater flexion of the knee in a more natural way by promoting or at least accommodating internal tibial rotation in a controlled way, replication of the natural screw home mechanism, and controlled articulation of the tibia and femur respective to each other in a more natural way. In a preferred embodiment, such prostheses include an insert component disposed between a femoral component and a tibial component, the insert component preferably featuring among other things a reversely contoured posterolateral bearing surface that helps impart internal rotation to the tibia as the knee flexes. Other surfaces can also be specially shaped to achieve similar results, preferably using iterative automated techniques that allow testing and iterative design taking into account a manageable set of major forces acting on the knee during normal functioning, together with information that is known about natural knee joint kinetics and kinematics." The patent application was filed on Nov. 23, 2010 (12/952,648). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,148.PN.&OS=PN/83,94,148&RS=PN/83,94,148 Written by Amal Ahmed; edited by Jaya Anand. *** University of California Assigned Patent for Optical Determination of Glucose Utilizing Boronic Acid Adducts ALEXANDRIA, Va., March 16 -- The University of California, Oakland, Calif., has been assigned a patent (8,394,357) developed by Bakthan Singaram, Santa Cruz, Calif., and Ritchie A. Wessling, Watsonville, Calif., for an "optical determination of glucose utilizing boronic acid adducts." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being." The patent application was filed on Aug. 8, 2008 (12/189,082). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,357&OS=8,394,357&RS=8,394,357 Written by Arpi Sharma; edited by Anand Kumar. *** Spartek Medical Assigned Patent ALEXANDRIA, Va., March 16 -- Spartek Medical, Concord, Calif., has been assigned a patent (8,394,127) developed by seven co-inventors for a "low profile spinal prosthesis incorporating a bone anchor having a deflectable post and a compound spinal rod." The co-inventors are Charles J. Winslow, Lafayette, Calif., Steven T. Mitchell, Pleasant Hill, Calif., John J. Flynn, Walnut Creek, Calif., James F. Zucherman, San Francisco, Ken Y. Hsu, San Francisco, Henry A. Klyce, San Francisco, and H. Adam R. Klyce, Berkeley, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "A bone anchor comprising a self-centering ball-joint suitable for use in a spine stabilization prosthesis which supports the spine while providing for the preservation of spinal motion. The bone anchor has a deflectable ball-rod partially received in a socket of a housing formed in the head of the bone anchor. A centering rod received partially in the ball-rod and partially within the housing operates to align the ball-rod with the longitudinal axis of the bone anchor. Deflection of the ball-rod bends the centering rod which in turn applies a restoring force upon the ball-rod." The patent application was filed on June 27, 2012 (13/535,045). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,127.PN.&OS=PN/83,94,127&RS=PN/83,94,127 Written by Amal Ahmed; edited by Jaya Anand. *** Coalign Innovations Assigned Patent ALEXANDRIA, Va., March 16 -- Coalign Innovations, Brisbane, Calif., has been assigned a patent (8,394,143) developed by Thomas Grotz, San Francisco, and Rudy Pretti, Auburn, Calif., for a "selectively expanding spine cage, hydraulically controllable in three dimensions for enhanced spinal fusion." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A selectively expanding spine cage has a minimized diameter in its unexpanded state that is smaller than the diameter of the neuroforamen through which it passes in the distracted spine. Hydraulic extension of extendable members permit the cage to conformably engage between vertebral bodies to effectively distract the disc space and rigidly fix the spine." The patent application was filed on Oct. 31, 2007 (11/981,150). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,143.PN.&OS=PN/83,94,143&RS=PN/83,94,143 Written by Amal Ahmed; edited by Jaya Anand. *** Interventional Spine Assigned Patent ALEXANDRIA, Va., March 16 -- Interventional Spine, Irvine, Calif., has been assigned a patent (8,394,129) developed by Rudolf Morgenstern Lopez, Barcelona, Spain, Robert Flower, Sun City, Calif., and Christopher Warren, Aliso Viejo, Calif., for a "method and apparatus for minimally invasive insertion of intervertebral implants." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A dilation introducer for orthopedic surgery is provided for minimally invasive access for insertion of an intervertebral implant. The dilation introducer may be used to provide an access position through Kambin's triangle from a posterolateral approach. A first dilator tube with a first longitudinal axis is provided. A second dilator tube may be introduced over the first, advanced along a second longitudinal axis parallel to but offset from the first. A third dilator tube may be introduced over the second, advanced along a third longitudinal axis parallel to but offset from both the first and the second. An access cannula may be introduced over the third dilator tube. With the first, second, and third dilator tubes removed, surgical instruments may pass through the access cannula to operate on an intervertebral disc and/or insert an intervertebral implant." The patent application was filed on Sept. 26, 2011 (13/245,130). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,129.PN.&OS=PN/83,94,129&RS=PN/83,94,129 Written by Amal Ahmed; edited by Jaya Anand. *** Smith & Nephew, University of Pennsylvania Assigned Patent for High Performance Femoral Knee Prostheses ALEXANDRIA, Va., March 16 -- Smith & Nephew, Memphis, Tenn., and the University of Pennsylvania, Philadelphia, have been assigned a patent (8,394,147) developed by eight co-inventors for "high performance femoral knee prostheses." The co-inventors are Jason Otto, Memphis, Tenn., Brian McKinnon, Bartlett, Tenn., Dean Hughes, Memphis, Tenn., Michael Ries, Tiberon, Calif., Jan Victor, Brugge, Belgium, Johan Bellemans, Langdorp, Belgium, Jonathan Garino, Villanova, Pa., and Timothy Wilton, Duffield, United Kingdom. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Knee prostheses featuring components that more faithfully replicate the structure and function of the human knee joint in order to provide, among other benefits: greater flexion of the knee in a more natural way by promoting or at least accommodating internal tibial rotation in a controlled way, replication of the natural screw home mechanism, and controlled articulation of the tibia and femur respective to each other in a more natural way. In a preferred embodiment, such prostheses include an insert component disposed between a femoral component and a tibial component, the insert component preferably featuring among other things a reversely contoured posterolateral bearing surface that helps impart internal rotation to the tibia as the knee flexes. Other surfaces can also be specially shaped to achieve similar results, preferably using iterative automated techniques that allow testing and iterative design taking into account a manageable set of major forces acting on the knee during normal functioning, together with information that is known about natural knee joint kinetics and kinematics." The patent application was filed on Nov. 23, 2010 (12/952,667). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,147.PN.&OS=PN/83,94,147&RS=PN/83,94,147 Written by Amal Ahmed; edited by Jaya Anand. *** Neotract Assigned Patent ALEXANDRIA, Va., March 16 -- Neotract, Pleasanton, Calif., has been assigned a patent (8,394,113) developed by Michael Wei, Redwood City, Calif., Theodore C. Lamson, Pleasanton, Calif., and Joseph Catanese III, San Leandro, Calif., for a coiled anchor device. The abstract of the patent published by the U.S. Patent and Trademark Office states: "A coiled anchor that secures to a connector as part of an anchor assembly is disclosed. The coiled anchor includes windings which capture and deform the connector between the windings and prevent the connector from disengaging from the coiled anchor once engaged." The patent application was filed on Aug. 9, 2010 (12/852,729). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,113.PN.&OS=PN/83,94,113&RS=PN/83,94,113 Written by Amal Ahmed; edited by Jaya Anand. *** Alphatec Spine Assigned Patent ALEXANDRIA, Va., March 16 -- Alphatec Spine, Carlsbad, Calif., has been assigned a patent (8,394,109) developed by Clark Hutton, San Clemente, Calif., and Ketchen Smith, Escondido, Calif., for "systems and methods for spinal fixation." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A spinal stabilization system, method, and a surgical kit having a surgical extender apparatus for implanting a surgical screw are disclosed. The extender includes a housing having a distal end and a proximal end, a hollow interior passageway disposed between the distal end and the proximal end, a channel disposed along an exterior surface of the housing at least partially between the distal end and the proximal end and configured to at least partially expose the hollow interior passageway, an interior locking mechanism disposed on an interior surface of the housing and substantially adjacent the proximal end, wherein the interior locking mechanism is configured to allow attachment of at least one surgical tool, and at least one flexible member disposed substantially adjacent the distal end. The housing is configured to accommodate placement of a surgical screw implant. The surgical screw implant is secured to the housing using a mating feature in the surgical screw implant. The at least one flexible member is configured to retain the surgical screw implant. The mating feature is configured to control axial movement of the surgical screw implant." The patent application was filed on Aug. 11, 2009 (12/462,974). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,109.PN.&OS=PN/83,94,109&RS=PN/83,94,109 Written by Amal Ahmed; edited by Jaya Anand. *** Simpirica Spine Assigned Patent ALEXANDRIA, Va., March 16 -- Simpirica Spine, San Carlos, Calif., has been assigned a patent (8,394,128) developed by four co-inventors for a "modulated constraining apparatus and methods of use." The co-inventors are Manish Kothari, San Rafael, Calif., Louis Fielding, San Carlos, Calif., Colin Cahill, Portola Valley, Calif., and Anand Parikh, San Diego. The abstract of the patent published by the U.S. Patent and Trademark Office states: "A constraining apparatus includes a constraining structure that captures a first and a second anatomical structure. A motion limiting member coupled with the constraining structure is adapted to provide a force resistant to relative movement of the first anatomical structure away from the second anatomical structure. A regulating member is detachably coupled with the motion limiting member or the constraining structure and is adapted to change the resistant force provided by the motion limiting member when the regulating member is in direct engagement with the motion limiting member or constraining structure." The patent application was filed on April 27, 2011 (13/095,586). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,128.PN.&OS=PN/83,94,128&RS=PN/83,94,128 Written by Amal Ahmed; edited by Jaya Anand. *** Lawrence Livermore National Security Assigned Patent for Catalyst Functionalized Buffer Sorbent Pebbles for Rapid Separation of Carbon Dioxide from Gas Mixtures ALEXANDRIA, Va., March 16 -- Lawrence Livermore National Security, Livermore, Calif., has been assigned a patent (8,394,350) developed by Roger D. Aines, Livermore, Calif., for a "catalyst functionalized buffer sorbent pebbles for rapid separation of carbon dioxide from gas mixtures." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A method for separating CO.sub.2 from gas mixtures uses a slurried media impregnated with buffer compounds and coating the solid media with a catalyst or enzyme that promotes the transformation of CO.sub.2 to carbonic acid. Buffer sorbent pebbles with a catalyst or enzyme coating are provided for rapid separation of CO.sub.2 from gas mixtures." The patent application was filed on May 19, 2010 (12/783,394). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,350&OS=8,394,350&RS=8,394,350 Written by Arpi Sharma; edited by Anand Kumar. *** W.L. Gore & Associates Assigned Patent ALEXANDRIA, Va., March 16 -- W.L. Gore & Associates, Flagstaff, Ariz., has been assigned a patent (8,394,121) developed by Stephanie M. Kladakis, Stoneham, Mass., and Robert L. Cafferata, Santa Rosa, Calif., for an "intracardiac implant for delivery of alarmins and methods thereof." The abstract of the patent published by the U.S. Patent and Trademark Office states: "The invention provides a cardiovascular occluder for treating a cardiovascular abnormality comprising a frame and an alarmin or an alarmin activator bound to the surface of the frame. The invention further provides methods of manufacturing the cardiovascular occluder and methods of treating cardiovascular abnormalities by delivering the cardiovascular occlude." The patent application was filed on Jan. 12, 2009 (12/352,281). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,121.PN.&OS=PN/83,94,121&RS=PN/83,94,121 Written by Amal Ahmed; edited by Jaya Anand. *** Medtronic Assigned Patent ALEXANDRIA, Va., March 16 -- Medtronic, Minneapolis, has been assigned a patent (8,394,114) developed by Laurent Schaller, Los Altos, Calif., Liem Ho, Mountain View, Calif., and Tom Breton, Palo Alto, Calif., for a "surgical connection apparatus and methods." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Surgical connection apparatus comprises a support structure, a plurality of clips, which can be self-closing clips, each clip being releasably coupled to the support structure, and a plurality of barbs, each barb being coupled to the support structure, the barbs being separate from the clips, which are ejectable from the support structure independently of the barbs." The patent application was filed on Sept. 26, 2003 (10/672,009). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,114.PN.&OS=PN/83,94,114&RS=PN/83,94,114 Written by Amal Ahmed; edited by Jaya Anand. *** AirXpanders, Shalon Ventures Assigned Patent ALEXANDRIA, Va., March 16 -- AirXpanders, Palo Alto, Calif., and Shalon Ventures, Palo Alto, Calif., have been assigned a patent (8,394,118) developed by seven co-inventors for "tissue expanders and methods of use." The co-inventors are Christopher S. Jones, Menlo Park, Calif., Daniel Jacobs, Palo Alto, Calif., F. Mark Payne, Palo Alto, Calif., David S. Mintz, Mountain View, Calif., Craig A. Purdy, Campbell, Calif., Ryan S. Han, Saratoga, Calif., and Tadmor Shalon, Palo Alto, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Tissue expanders and their methods of use." The patent application was filed on Dec. 7, 2011 (13/313,904). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,118.PN.&OS=PN/83,94,118&RS=PN/83,94,118 Written by Amal Ahmed; edited by Jaya Anand. *** Neotract Assigned Patent ALEXANDRIA, Va., March 16 -- Neotract, Pleasanton, Calif., has been assigned a patent (8,394,110) developed by eleven co-inventors for an "apparatus and method for manipulating or retracting tissue and anatomical structure." The co-inventors are Joseph Catanese III, San Leandro, Calif., Theodore C. Lamson, Pleasanton, Calif., Joshua Makower, Los Altos, Calif., Amik Nagpurkar, Toronto, Daniel Merrick, Dublin, Calif., Jacqueline Nerney Welch, Moraga, Calif., Richard G. Vecchiotti, Stanford, Calif., Scott West, Livermore, Calif., Claude Vidal, Santa Barbara, Calif., Russell J. Redmond, Goleta, Calif., and Michael Collinson, Gelta, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Integrated systems and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchoring devices for such purposes." The patent application was filed on Feb. 28, 2011 (13/037,097). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=83,94,110.PN.&OS=PN/83,94,110&RS=PN/83,94,110 Written by Amal Ahmed; edited by Jaya Anand. *** HHS Assigned Patent ALEXANDRIA, Va., March 16 -- The U.S. Department of Health and Human Services has been assigned a patent (8,394,764) developed by Michael R. Boyd, Mobile, Ala., Toshiyuki Mori, San Francsico, and Barry R. O'Keefe, Frederick, Md., for "griffithsin, glycosylation-resistant griffithsin, and related conjugates, compositions, nucleic acids, vectors, host cells, methods of production and methods of use." The abstract of the patent published by the U.S. Patent and Trademark Office states: "An isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 3, wherein the at least eight contiguous amino acids have anti-viral activity, as well as an isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 3, wherein the at least eight contiguous amino acids have anti-viral activity, and, when the at least eight contiguous amino acids comprise amino acids 1-121 of SEQ ID NO: 3, the at least eight contiguous amino acids have been rendered glycosylation-resistant, a vector comprising such an isolated and purified nucleic acid molecule, a host cell comprising the nucleic acid molecule, optionally in the form of a vector, a method of producing an anti-viral polypeptide or conjugate thereof, the anti-viral polypeptide itself, a conjugate or fusion protein comprising the anti-viral polypeptide, and compositions comprising an effective amount of the anti-viral polypeptide or conjugate or fusion protein thereof. Further provided are methods of inhibiting prophylactically or therapeutically a viral infection of a host." The patent application was filed on Feb. 7, 2011 (13/022,289). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,764&OS=8,394,764&RS=8,394,764 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Spectrum Pharmaceuticals, University of Illinois Assigned Patent ALEXANDRIA, Va., March 16 -- Spectrum Pharmaceuticals, Irvine, Calif., and the University of Illinois, Urbana, Ill., have been assigned a patent (8,394,757) developed by Anil Gulati, Naperville, Ill., Guru Reddy, Irvine, Calif., and Luigi Lenaz, Newton, Pa., for "sensitization of tumor cells to radiation therapy through the administration of endothelin agonists." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Methods to sensitize tumor cells to radiation therapy through the administration of an endothelin agonist such as the ET.sub.B agonist IRL1620." The patent application was filed on Aug. 27, 2007 (11/845,648). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,757&OS=8,394,757&RS=8,394,757 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Allergan Assigned Patent ALEXANDRIA, Va., March 16 -- Allergan, Irvine, Calif., has been assigned a patent (8,394,782) developed by Dimitrios Stroumpoulis, Goleta, Calif., Christopher S. Mudd, Goleta, Calif., and Ahmet Tezel, Goleta, Calif., for a "polysaccharide gel formulation having increased longevity." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide. In some embodiments, the incorporating step comprises 1) mixing the at least one inhibitor with the at least one polysaccharide at a highly hydrated state thereby encapsulating the at least one inhibitor in a polysaccharide network, and 2) dehydrating the polysaccharide network thereby controlling release kinetics or final swell ratio. In another embodiment, the incorporating step comprises 1) encapsulating at least one inhibitor into a biocompatible or biodegradable vessel and 2) combining the polysaccharide and the vessel into a gel formulation. The polysaccharide gel formulations described herein can be used for a variety of cosmetic applications." The patent application was filed on Nov. 21, 2008 (12/276,167). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,782&OS=8,394,782&RS=8,394,782 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Cymbiotics Assigned Patent ALEXANDRIA, Va., March 16 -- Cymbiotics, Escondido, Calif., has been assigned a patent (8,394,759) developed by Raj R. Barathur, Escondido, Calif., and Jack Bain Bookout, San Diego, for "transdermal delivery of medicaments with combinations of cetylated fatty ester penetrant complexes." The abstract of the patent published by the U.S. Patent and Trademark Office states: "This invention describes a topical delivery mechanism that contains a mixture of cetylated fatty esters that act as transdermal carriers of desired therapeutic molecules. The proposed cetyl fatty ester penetrant-complex (Base CFEP-complex) contains specific cetyl fatty esters, polar solvents, a carrier base (gel, cream, lotion, patch or stick gel), antioxidants and the desired pharmaceutical, cosmetic or antigenic response eliciting molecules that are efficaciously delivered by selectively varying component ratios in the complex. The invention proposes the use of transdermal delivery of medications such as those used in treatment of urinary incontinence, testosterone deficiency, arthritic and joint pain and other pains such as pain in the neck, lower back, back, knees, headaches, and other types of inflammatory pains, peripheral neuropathic pain, pain associated with repetitive strain injuries such as myofacial pain, rapid treatment of epileptic seizures, soluble antigens in the immuno-therapeutic treatment of allergies, actives in the treatment of foot cracks and elbow cracks, actives in the treatment of facial and other wrinkles in the form of anti-aging creams and gels and other topically delivered therapies." The patent application was filed on Oct. 29, 2009 (12/608,963). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,759&OS=8,394,759&RS=8,394,759 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** University of California Assigned Patent ALEXANDRIA, Va., March 16 -- The University of California, Oakland, Calif., has been assigned a patent (8,394,788) developed by Alan S. Verkman, San Francisco, and Marc Harris Levin, San Francisco, for "phenylsulfoxyoxazole compound inhibitors of urea transporters." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Provided herein are small molecule compounds that alter the transport activity of solute transporters, particularly urea transporters. The compounds described herein belong to the phenylsulfoxyoxazole, phenylsulfoxyimidazole, phenylsulfoxythiazole class of compounds. The compounds described herein are useful for increasing solute clearance in states of fluid overload and for treating cardiovascular, renal, and metabolic diseases, disorders, and conditions. Methods for identifying and using these agents that inhibit urea transporters are described herein." The patent application was filed on Nov. 16, 2007 (12/515,000). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,788&OS=8,394,788&RS=8,394,788 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Amylin Pharmaceuticals, AstraZeneca Pharmaceuticals Assigned Patent ALEXANDRIA, Va., March 16 -- Amylin Pharmaceuticals, San Diego, and AstraZeneca Pharmaceuticals, Wilmington, Del., have been assigned a patent (8,394,765) developed by Jonathan D. Roth, San Diego, Christen M. Anderson, Encinitas, Calif., and Alain D. Baron, San Diego, for "methods of treating obesity with two different anti-obesity agents." The abstract of the patent published by the U.S. Patent and Trademark Office states: "Methods for treating obesity or obesity related disorders are disclosed. These methods include the use of anti-obesity agents directed to the forebrain in combination with anti-obesity agents directed to the hindbrain." The patent application was filed on Nov. 14, 2007 (11/940,317). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,765&OS=8,394,765&RS=8,394,765 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Lam Research Assigned Patent ALEXANDRIA, Va., March 16 -- Lam Research, Fremont, Calif., has been assigned a patent (8,394,722) developed by Gerardo A. Delgadino, Santa Clara, Calif., and Robert C. Hefty, Fremont, Calif., for a "bi-layer, tri-layer mask CD control." The abstract of the patent published by the U.S. Patent and Trademark Office states: "A method for controlling critical dimension (CD) of etch features in an etch layer disposed below a functionalized organic mask layer disposed below an intermediate mask layer, disposed below a patterned photoresist mask, which forms a stack is provided. The intermediate mask layer is opened by selectively etching the intermediate mask layer with respect to the patterned photoresist mask. The functionalized organic mask layer is opened. The functionalized organic mask layer opening comprises flowing an open gas comprising COS, forming a plasma, and stopping the flowing of the open gas. The etch layer is etched." The patent application was filed on Nov. 3, 2008 (12/263,662). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,722&OS=8,394,722&RS=8,394,722 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Allergan Assigned Patent for Polysaccharide Gel Formulation Having Multi-stage Bioactive Agent Delivery ALEXANDRIA, Va., March 16 -- Allergan, Irvine, Calif., has been assigned a patent (8,394,783) developed by four co-inventors for a "polysaccharide gel formulation having multi-stage bioactive agent delivery." The co-inventors are Dimitrios Stroumpoulis, Goleta, Calif., Dustin Leslie, Santa Barbara, Calif., Christopher S. Mudd, Ventura, Calif., and Ahmet Tezel, Santa Barbara, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide." The patent application was filed on April 4, 2012 (13/439,566). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=8,394,783&OS=8,394,783&RS=8,394,783 Written by Satyaban Rath; edited by Hemanta Panigrahi. *** Array BioPharma, Genentech Assigned Patent ALEXANDRIA, Va., March 16 -- Array BioPharma, Boulder, Colo., and Genentech, South San Francisco, Calif., have been assigned a patent (8,394,795) developed by 20 co-inventors for "pyrazole [3, 4-B] pyridine Raf inhibitors." The co-inventors are Kateri A. Ahrendt, Boulder, Colo., Alexandre J. Buckmelter, Boulder, Colo., Jason De Meese, Boulder, Colo., Jonas Grina, Boulder, Colo., Joshua D. Hansen, Boulder, Colo., Ellen R. Laird, Boulder, Colo., Paul Lunghofer, Boulder, Colo., David Moreno, Boulder, Colo., Brad Newhouse, Boulder, Colo., Li Ren, Boulder, Colo., Jeongbeob Seo, Boulder, Colo., Hongqi Tian, Boulder, Colo., Steven Mark Wenglowsky, Boulder, Colo., Bainian Feng, South San Francisco, Calif., Janet Gunzner, South San Francisco, Calif., Kim Malesky, South San Francisco, Calif., Simon Mathieu, South San Francisco, Calif., Joachim Rudolph, South San Francisco, Calif., Zhaoyang Wen, South San Francisco, Calif., and Wendy B. Young, South San Francisco, Calif. The abstract of the patent published by the U.S. Patent and Trademark Office states: "Compounds of Formula I are useful for inhibition of Raf kinases. Methods of using compounds of Formula I and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. ##STR00001##" The patent application was filed on Feb. 27, 2009 (12/920,050). The full-text of the patent can be found at http://patft.uspto.gov/netacgi/nph-Parser Sect1=PTO2& For more information about Targeted News Service products and services, please contact: Myron Struck, editor, Targeted News Service LLC, Springfield, Va., 703/304-1897; [email protected]; http://targetednews.com. -1117989 (c) 2013 Targeted News Service |