|[October 04, 2013]
Inventages Portfolio Company, Cognoptix, Demonstrates the Ability to Accurately Identify Alzheimer's Disease
LONDON --(Business Wire)--
announces that one of its portfolio companies, Cognoptix,
has demonstrated unprecedented accuracy in detecting Alzheimer's
disease. A multi-site clinical trial of the SAPPHIRE II eye test showed
a sensitivity of 85% and a specificity of 95% in differentiating
Alzheimer's disease patients from healthy volunteers.
The Cognoptix test involves a simple eye test that detects beta-amyloid,
the hallmark of Alzheimer's disease. This test is significantly
differentiated from other blood or imaging tests in being:
Simple and non-invasive to perform
Quick, taking less than 5 minutes
Detects the defining hallmark of Alzheimer's disease, not a surrogate
Generates an easy to interpret result
Cost effective (costing a fraction of the cost of PET imaging)
These unique features will enable the widespread use of the SAPPHIRE II
system in non-specialist centers with the potential of becoming a much
needed early detection system for Alzheimer's disease.
"These linical results give us a great deal of hope that we will
eventually be able to intervene early in the course of Alzheimer's
disease, well ahead of the manifestation of symptoms," said Maria C.
Carrillo, Ph.D., Vice President, Medical and Scientific Relations,
Alzheimer's Association. "The Cognoptix eye test is designed to be a
simple but reliable system of early-stage diagnosis to allow treatment
before significant neuronal loss and irreversible brain damage occurs,"
said Paul Hartung, President and CEO of Cognoptix.
"Due to the huge unmet clinical need, Inventages has a strong interest
in brain health and in particular Alzheimer's disease. We recognize that
early detection is critical to the better management of Alzheimer's
patients and the development of new drugs. Consequently, we are very
excited by these unprecedented results and by the potential impact that
this simple office-based test could have on this terrible disease.
Particular credit should be given to the Cognoptix team who has always
strived for excellence in this challenging indication," said Dr Gunnar
Weikert, Managing partner of Inventages and Cognoptix Board Director.
The study results will be presented at the Clinical Trials Conference on
Alzheimer's disease (CTAD) in November 2013
Inventages Venture Capital (www.inventages.com),
one of the world's largest life science venture capital firms, focuses
on products for the management chronic diseases. Brain health is core
within Inventages' investment focus, in particular the huge unmet
clinical need of Alzheimer's disease. Inventages has also invested in Accera,
a Colorado-based company that has developed a novel therapeutic (Axona™)
for the management of Alzheimer's disease (www.about-axona.com).
a privately held medical technology company headquartered in
Massachusetts, is focused on developing and commercializing an
in-office, drug/device diagnostic system as an aid in the early
detection of Alzheimer's disease.
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