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High-Throughput Screening: Technologies and Global MarketsNEW YORK, Jan. 21, 2019 /PRNewswire/ -- Report Scope: Summary The global high-throughput screening (HTS) market is expected to reach REDACTED by 2023 at a CAGR of REDACTED during the forecast period.HTS was invented in 1951 by Dr. Gyula Takatsky; six rows of 12 wells in Lucite were machined to develop the first microtiter plate.Technology and approaches for HTS have advanced in the last few years. High-throughput screening is a modern technique used in drug development that can be applied in the biological and chemical sciences. The application of robots, detectors, sensors and software enables a variety of analyses of chemical and biological compounds. This analysis can be conducted in a short time, and the toxicity of biological structures and characteristics of metabolic and pharmacokinetic processes can be determined. HTS aims to lead discovery for both pharmaceutical and agrochemical applications.The primary goal for pharmaceutical companies is to restructure drug discovery programs to develop the highest -performing drugs. Companies are prioritizing innovation in HTS as a major strategy in an increasingly competitive environment.The latest developments in molecular biology, chemistry, pharmacology, laboratory automation, bioinformatics and computing enable the discovery of new and innovative drugs. Furthermore, HTS enables the determination of cytotoxicity, which leads to significant decreases in expenditures and reductions in the length of the study. HTS has become a key tool for companies and research industries, due to its ability to test large numbers of compounds quickly and efficiently.There are also opportunities for companies that can identify and implement new technology effectively. Effective integration of compound supply, assay operation and data management are essential to achieve necessary productivity. HTS is an advanced technology initiative that can utilize the advantages of the latest advances in bioscience, biotechnology, engineering and information science. A rising number of drug targets for screening, the large numbers of reagents and assay kits used in HTS techniques and increasing pharmaceutical R&D are boosting the market. Additionally, considerable investments by government and research institutes in drug discovery are other factors that will drive the HTS market in the future. High-throughput screening enables researchers to screen huge chemical libraries against a growing number of targets for lead discovery. Drug discovery is significantly relying on both HTS and uHTS screening capability, as well as the automation technology. Ultra-high-throughput screening is defined as screening more than 100,000 generated data points per day. Laboratory automation has grown from a novel technology to being widely used in combination with HTS technology.Applications of laboratory automation include sample generation and preparation, genomics and proteomics for target finding and validation, robotic storage devices, automated multiple parallel synthesis stations, parallel liquid handling systems, workstations and fully integrated robots for primary biological screening. Technological advancement in automation will expand the number of hits and be beneficial in hit discovery, hit profiling, pharmacological testing, re-synthesis in gram quantities and in vivo profiling.Further, artificial intelligence has the ability to analyze large amounts of data generated during biological research. Artificial intelligence enables drug discovery for rare and neglected disease by utilizing HTS datasets and machine learning models in order to identify molecules for further testing. The machine learning models have already been used for identifying lead molecules for tuberculosis therapies. Read the full report: https://www.reportlinker.com/p05724855 About Reportlinker ReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place. __________________________ Contact Clare: [email protected] US: (339)-368-6001 Intl: +1 339-368-6001 View original content:http://www.prnewswire.com/news-releases/high-throughput-screening-technologies-and-global-markets-300781550.html SOURCE Reportlinker |